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SMARCB1 loss induces druggable cyclin D1 deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors.
Xue, Yibo; Zhu, Xianbing; Meehan, Brian; Venneti, Sriram; Martinez, Daniel; Morin, Geneviève; Maïga, Rayelle I; Chen, Hongbo; Papadakis, Andreas I; Johnson, Radia M; O'Sullivan, Maureen J; Erdreich-Epstein, Anat; Gotlieb, Walter H; Park, Morag; Judkins, Alexander R; Pelletier, Jerry; Foulkes, William D; Rak, Janusz; Huang, Sidong.
Affiliation
  • Xue Y; Department of Biochemistry, McGill University, Montreal, Canada.
  • Zhu X; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Meehan B; Department of Biochemistry, McGill University, Montreal, Canada.
  • Venneti S; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Martinez D; Department of Pediatrics, McGill University, and Research Institute of McGill University Health Centre, Montreal Children's Hospital, Montreal, Canada.
  • Morin G; Pathology and Neuropathology, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Maïga RI; Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, USA.
  • Chen H; Department of Biochemistry, McGill University, Montreal, Canada.
  • Papadakis AI; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Johnson RM; Department of Biochemistry, McGill University, Montreal, Canada.
  • O'Sullivan MJ; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Erdreich-Epstein A; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou, PR China.
  • Gotlieb WH; Department of Biochemistry, McGill University, Montreal, Canada.
  • Park M; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Judkins AR; Department of Biochemistry, McGill University, Montreal, Canada.
  • Pelletier J; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Foulkes WD; School of Medicine, University of Dublin, Trinity College, Dublin, Ireland.
  • Rak J; Children's Health Ireland at Crumlin, Dublin, Ireland.
  • Huang S; Departments of Pediatrics and Pathology, The Saban Research Institute at Children's Hospital Los Angeles and the Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.
J Pathol ; 252(1): 77-87, 2020 09.
Article in En | MEDLINE | ID: mdl-32558936
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Teratoma / Proteins / Gene Expression Regulation, Neoplastic / Rhabdoid Tumor / Cyclin D1 / SMARCB1 Protein Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Pathol Year: 2020 Type: Article Affiliation country: Canada
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Teratoma / Proteins / Gene Expression Regulation, Neoplastic / Rhabdoid Tumor / Cyclin D1 / SMARCB1 Protein Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Pathol Year: 2020 Type: Article Affiliation country: Canada