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Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia.
Abdelrasoul, Hend; Vadakumchery, Anila; Werner, Markus; Lenk, Lennart; Khadour, Ahmad; Young, Marc; El Ayoubi, Omar; Vogiatzi, Fotini; Krämer, Markus; Schmid, Vera; Chen, Zhengshan; Yousafzai, Yasar; Cario, Gunnar; Schrappe, Martin; Müschen, Markus; Halsey, Christina; Mulaw, Medhanie A; Schewe, Denis M; Hobeika, Elias; Alsadeq, Ameera; Jumaa, Hassan.
Affiliation
  • Abdelrasoul H; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany.
  • Vadakumchery A; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany.
  • Werner M; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany.
  • Lenk L; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Khadour A; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany.
  • Young M; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany.
  • El Ayoubi O; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany.
  • Vogiatzi F; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Krämer M; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany.
  • Schmid V; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany.
  • Chen Z; Department of Systems Biology and City of Hope Comprehensive Cancer Center, Monrovia, CA, USA.
  • Yousafzai Y; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  • Cario G; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Schrappe M; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Müschen M; Department of Systems Biology and City of Hope Comprehensive Cancer Center, Monrovia, CA, USA.
  • Halsey C; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  • Mulaw MA; Institute of Experimental Cancer Research, Medical Faculty, University of Ulm, Ulm, Germany.
  • Schewe DM; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.
  • Hobeika E; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany.
  • Alsadeq A; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany.
  • Jumaa H; Institute of Immunology, Ulm University Medical Center, 89081, Ulm, Germany. hassan.jumaa@uni-ulm.de.
Nat Commun ; 11(1): 3194, 2020 06 24.
Article in En | MEDLINE | ID: mdl-32581241
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Philadelphia Chromosome / Fusion Proteins, bcr-abl / Receptors, CXCR4 / Interleukin-7 Receptor alpha Subunit / Precursor Cell Lymphoblastic Leukemia-Lymphoma Limits: Animals / Female / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Philadelphia Chromosome / Fusion Proteins, bcr-abl / Receptors, CXCR4 / Interleukin-7 Receptor alpha Subunit / Precursor Cell Lymphoblastic Leukemia-Lymphoma Limits: Animals / Female / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Type: Article Affiliation country: Germany