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Efficacy of Novel Pyrazolone Phosphodiesterase Inhibitors in Experimental Mouse Models of Trypanosoma cruzi.
de Araújo, Julianna Siciliano; França da Silva, Cristiane; Batista, Denise da Gama Jaén; Nefertiti, Aline; Fiuza, Ludmila Ferreira de Almeida; Fonseca-Berzal, Cristina Rosa; Bernardino da Silva, Patrícia; Batista, Marcos Meuser; Sijm, Maarten; Kalejaiye, Titilola D; de Koning, Harry P; Maes, Louis; Sterk, Geert Jan; Leurs, Rob; Soeiro, Maria de Nazaré Correia.
Affiliation
  • de Araújo JS; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • França da Silva C; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Batista DDGJ; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Nefertiti A; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Fiuza LFA; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Fonseca-Berzal CR; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Bernardino da Silva P; Departamento de Parasitología, Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain.
  • Batista MM; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Sijm M; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Kalejaiye TD; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam, Amsterdam, The Netherlands.
  • de Koning HP; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Maes L; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Sterk GJ; Laboratory for Microbiology, Parasitology and Hygiene, University of Antwerp, Antwerp, Belgium.
  • Leurs R; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam, Amsterdam, The Netherlands.
  • Soeiro MNC; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam, Amsterdam, The Netherlands.
Antimicrob Agents Chemother ; 64(9)2020 08 20.
Article in En | MEDLINE | ID: mdl-32601163
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanocidal Agents / Trypanosoma cruzi / Chagas Disease / Pyrazolones / Nitroimidazoles Limits: Animals Language: En Journal: Antimicrob Agents Chemother Year: 2020 Type: Article Affiliation country: Brazil
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanocidal Agents / Trypanosoma cruzi / Chagas Disease / Pyrazolones / Nitroimidazoles Limits: Animals Language: En Journal: Antimicrob Agents Chemother Year: 2020 Type: Article Affiliation country: Brazil