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IQGAP1 promotes anoikis resistance and metastasis through Rac1-dependent ROS accumulation and activation of Src/FAK signalling in hepatocellular carcinoma.
Mo, Chun-Fen; Li, Jun; Yang, Shu-Xia; Guo, Hui-Jie; Liu, Yang; Luo, Xing-Yan; Wang, Yan-Tang; Li, Min-Hui; Li, Jing-Yi; Zou, Qiang.
Affiliation
  • Mo CF; Department of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China. mochunfen@cmc.edu.cn.
  • Li J; Department of Gastroenterology, The first affiliated hospital of Chengdu medical college, Chengdu, China.
  • Yang SX; Department of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
  • Guo HJ; Department of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
  • Liu Y; Department of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
  • Luo XY; Department of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
  • Wang YT; Department of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
  • Li MH; Department of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
  • Li JY; Department of Urology, The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, China. lijingyi@cmc.edu.cn.
  • Zou Q; School of Biological Sciences and Technology, Chengdu Medical College, Chengdu, China. lijingyi@cmc.edu.cn.
Br J Cancer ; 123(7): 1154-1163, 2020 09.
Article in En | MEDLINE | ID: mdl-32632148
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reactive Oxygen Species / Carcinoma, Hepatocellular / Src-Family Kinases / Rac1 GTP-Binding Protein / Ras GTPase-Activating Proteins / Focal Adhesion Kinase 1 / Liver Neoplasms Limits: Animals / Female / Humans Language: En Journal: Br J Cancer Year: 2020 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reactive Oxygen Species / Carcinoma, Hepatocellular / Src-Family Kinases / Rac1 GTP-Binding Protein / Ras GTPase-Activating Proteins / Focal Adhesion Kinase 1 / Liver Neoplasms Limits: Animals / Female / Humans Language: En Journal: Br J Cancer Year: 2020 Type: Article Affiliation country: China