Preparation and Characterization of Nanostructured Lipid Carriers for Improved Topical Drug Delivery: Evaluation in Cutaneous Leishmaniasis and Vaginal Candidiasis Animal Models.

Riaz, Amina; Hendricks, Sarah; Elbrink, Kimberley; Guy, Caljon; Maes, Louis; Ahmed, Naveed; Kiekens, Filip; Khan, Gul Majid

Riaz, Amina; Hendricks, Sarah; Elbrink, Kimberley; Guy, Caljon; Maes, Louis; Ahmed, Naveed; Kiekens, Filip; Khan, Gul Majid.

Affiliation

Riaz A; Department of Pharmacy, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Hendricks S; Department of Pharmaceutical, Biomedical and Veterinary Sciences, Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, B-2610, Wilrijk, Belgium.
Elbrink K; Department of Pharmaceutical, Biomedical and Veterinary Sciences, Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, B-2610, Wilrijk, Belgium.
Guy C; Department of Pharmaceutical, Biomedical and Veterinary Sciences, Laboratory of Pharmaceutical Technology and Biopharmacy, University of Antwerp, Universiteitsplein 1, B-2610, Wilrijk, Belgium.
Maes L; Department of Pharmaceutical, Biomedical and Veterinary Sciences, Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, B-2610, Wilrijk, Belgium.
Ahmed N; Department of Pharmaceutical, Biomedical and Veterinary Sciences, Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, B-2610, Wilrijk, Belgium.
Kiekens F; Department of Pharmacy, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Khan GM; Department of Pharmaceutical, Biomedical and Veterinary Sciences, Laboratory of Pharmaceutical Technology and Biopharmacy, University of Antwerp, Universiteitsplein 1, B-2610, Wilrijk, Belgium.

AAPS PharmSciTech ; 21(5): 185, 2020 Jul 06.

Article in En | MEDLINE | ID: mdl-32632542

Subject(s)

Amphotericin B/administration & dosage; Candidiasis, Vulvovaginal/drug therapy; Leishmaniasis, Cutaneous/drug therapy; Nanostructures/administration & dosage; Administration, Topical; Animals; Candidiasis, Vulvovaginal/metabolism; Drug Carriers/administration & dosage; Drug Delivery Systems/methods; Drug Liberation; Female; Gels/metabolism; Humans; Lipids/administration & dosage; Male; Mice; Mice, Inbred BALB C; Models, Animal; Particle Size; Rats; Skin/metabolism; Skin Absorption

Key words

Amphotericin B; Nanoparticles; Nanostructured lipid carriers; Skin diseases; Topical

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candidiasis, Vulvovaginal / Amphotericin B / Leishmaniasis, Cutaneous / Nanostructures Limits: Animals / Female / Humans / Male Language: En Journal: AAPS PharmSciTech Journal subject: FARMACOLOGIA Year: 2020 Type: Article Affiliation country: Pakistan

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