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Two coupled mutations abolished the binding of CEBPB to the promoter of CXCL14 that displayed an antiviral effect on PRRSV by activating IFN signaling.
Niu, Lizhu; Zheng, Zhiwei; Xue, Qianjing; Cheng, Huijun; Liu, Ying; Wang, Huanling; Hu, Xueying; Zhang, Anding; Liu, Bang; Xu, Xuewen.
Affiliation
  • Niu L; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China.
  • Zheng Z; The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
  • Xue Q; Key Lab of Freshwater Animal Breeding, College of Fishery, Huazhong Agricultural University, Wuhan, China.
  • Cheng H; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China.
  • Liu Y; The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
  • Wang H; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China.
  • Hu X; The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
  • Zhang A; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China.
  • Liu B; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China.
  • Xu X; The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.
FASEB J ; 34(8): 11257-11271, 2020 08.
Article in En | MEDLINE | ID: mdl-32648265
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Promoter Regions, Genetic / Interferon-beta / Porcine respiratory and reproductive syndrome virus / Chemokines, CXC / CCAAT-Enhancer-Binding Protein-beta / Mutation Type of study: Prognostic_studies Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2020 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Promoter Regions, Genetic / Interferon-beta / Porcine respiratory and reproductive syndrome virus / Chemokines, CXC / CCAAT-Enhancer-Binding Protein-beta / Mutation Type of study: Prognostic_studies Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2020 Type: Article Affiliation country: China