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Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen.
Vardhana, Santosha A; Hwee, Madeline A; Berisa, Mirela; Wells, Daniel K; Yost, Kathryn E; King, Bryan; Smith, Melody; Herrera, Pamela S; Chang, Howard Y; Satpathy, Ansuman T; van den Brink, Marcel R M; Cross, Justin R; Thompson, Craig B.
Affiliation
  • Vardhana SA; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Hwee MA; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Berisa M; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
  • Wells DK; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Yost KE; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • King B; The Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Smith M; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.
  • Herrera PS; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA.
  • Chang HY; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Satpathy AT; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • van den Brink MRM; Department of Medicine and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Cross JR; Department of Medicine and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Thompson CB; Weill Cornell Medical College, New York, NY, USA.
Nat Immunol ; 21(9): 1022-1033, 2020 09.
Article in En | MEDLINE | ID: mdl-32661364
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes, Tumor-Infiltrating / CD8-Positive T-Lymphocytes / Mitochondria / Neoplasms Limits: Animals Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes, Tumor-Infiltrating / CD8-Positive T-Lymphocytes / Mitochondria / Neoplasms Limits: Animals Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Type: Article Affiliation country: United States