TNF-&#945;-dependent lung inflammation upregulates superoxide dismutase-2 to promote tumor cell proliferation in lung adenocarcinoma.

Han, Xiaojing; Liu, Xiaoyi; Wang, Xiuqing; Guo, Wenli; Wen, Yue; Meng, Wei; Peng, Daijun; Lv, Ping; Zhang, Xianghong; Shen, Haitao

TNF-α-dependent lung inflammation upregulates superoxide dismutase-2 to promote tumor cell proliferation in lung adenocarcinoma.

Han, Xiaojing; Liu, Xiaoyi; Wang, Xiuqing; Guo, Wenli; Wen, Yue; Meng, Wei; Peng, Daijun; Lv, Ping; Zhang, Xianghong; Shen, Haitao.

Affiliation

Han X; Laboratory of Pathology, Hebei Medical University, Shijiazhuang, China.
Liu X; Department of Basic Courses, NCO School, Army Medical University, Shijiazhuang, China.
Wang X; Laboratory of Pathology, Hebei Medical University, Shijiazhuang, China.
Guo W; Laboratory of Pathology, Hebei Medical University, Shijiazhuang, China.
Wen Y; Laboratory of Pathology, Hebei Medical University, Shijiazhuang, China.
Meng W; Laboratory of Pathology, Hebei Medical University, Shijiazhuang, China.
Peng D; Laboratory of Pathology, Hebei Medical University, Shijiazhuang, China.
Lv P; Laboratory of Pathology, Hebei Medical University, Shijiazhuang, China.
Zhang X; Department of Pharmacology, Hebei Medical University, Shijiazhuang, China.
Shen H; Laboratory of Pathology, Hebei Medical University, Shijiazhuang, China.

Mol Carcinog ; 59(9): 1088-1099, 2020 09.

Article in En | MEDLINE | ID: mdl-32673443

Subject(s)

Adenocarcinoma of Lung/pathology; Cell Proliferation; Lung Neoplasms/pathology; Pneumonia/complications; Superoxide Dismutase/metabolism; Tumor Necrosis Factor-alpha/metabolism; Urethane/toxicity; Adenocarcinoma of Lung/etiology; Adenocarcinoma of Lung/metabolism; Animals; Apoptosis; Carcinogens/toxicity; Cytokines; Female; Humans; Lung Neoplasms/etiology; Lung Neoplasms/metabolism; Macrophages/pathology; Mice; Mice, Inbred BALB C; Mice, Nude; Pneumonia/chemically induced; Pneumonia/metabolism; Tumor Cells, Cultured

Key words

SOD-2; TNF-α; lung adenocarcinoma; lung inflammation; macrophage

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia / Superoxide Dismutase / Urethane / Tumor Necrosis Factor-alpha / Cell Proliferation / Adenocarcinoma of Lung / Lung Neoplasms Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Carcinog Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2020 Type: Article Affiliation country: China

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