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A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands.
Grant, Emma K; Fallon, David J; Hann, Michael M; Fantom, Ken G M; Quinn, Chad; Zappacosta, Francesca; Annan, Roland S; Chung, Chun-Wa; Bamborough, Paul; Dixon, David P; Stacey, Peter; House, David; Patel, Vipulkumar K; Tomkinson, Nicholas C O; Bush, Jacob T.
Affiliation
  • Grant EK; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Fallon DJ; Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, UK.
  • Hann MM; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Fantom KGM; Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, UK.
  • Quinn C; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Zappacosta F; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Annan RS; GlaxoSmithKline, South Collegeville Road, Collegeville, PA, 19426, USA.
  • Chung CW; GlaxoSmithKline, South Collegeville Road, Collegeville, PA, 19426, USA.
  • Bamborough P; GlaxoSmithKline, South Collegeville Road, Collegeville, PA, 19426, USA.
  • Dixon DP; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Stacey P; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • House D; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Patel VK; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Tomkinson NCO; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
  • Bush JT; GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK.
Angew Chem Int Ed Engl ; 59(47): 21096-21105, 2020 11 16.
Article in En | MEDLINE | ID: mdl-32745361
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Quinoxalines / Sulfonamides / Bridged Bicyclo Compounds, Heterocyclic / Photoaffinity Labels / Cross-Linking Reagents / Vemurafenib / Antineoplastic Agents Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Angew Chem Int Ed Engl Year: 2020 Type: Article Affiliation country: United kingdom
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Quinoxalines / Sulfonamides / Bridged Bicyclo Compounds, Heterocyclic / Photoaffinity Labels / Cross-Linking Reagents / Vemurafenib / Antineoplastic Agents Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Angew Chem Int Ed Engl Year: 2020 Type: Article Affiliation country: United kingdom