Genetic ablation of Fas-activated serine/threonine kinase ameliorates obesity-related hepatic glucose and lipid metabolic disorders via sirtuin-1 signaling.

Zhang, Fuyang; Pei, Jianming; Chen, Xiyao

Zhang, Fuyang; Pei, Jianming; Chen, Xiyao.

Affiliation

Zhang F; Department of Cardiology, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, China; Department of Physiology and Pathophysiology, School of Basic Medicine, Air Force Medical University, Xi'an, Shaanxi, China.
Pei J; Department of Physiology and Pathophysiology, School of Basic Medicine, Air Force Medical University, Xi'an, Shaanxi, China. Electronic address: jmpei8@fmmu.edu.cn.
Chen X; Department of Geriatrics, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, China. Electronic address: cxyfmmu@163.com.

Biochem Biophys Res Commun ; 529(4): 1066-1072, 2020 09 03.

Article in En | MEDLINE | ID: mdl-32819566

Subject(s)

Gene Deletion; Glucose/metabolism; Lipid Metabolism Disorders/metabolism; Liver/metabolism; Obesity/metabolism; Protein Serine-Threonine Kinases/metabolism; Signal Transduction; Sirtuin 1/metabolism; Animals; Gluconeogenesis; Hepatocytes/metabolism; Lipogenesis; Mice; Palmitates

Key words

Fastk; Gluconeogenesis; Lipogenesis; Obesity; SIRT1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Protein Serine-Threonine Kinases / Gene Deletion / Lipid Metabolism Disorders / Sirtuin 1 / Glucose / Liver / Obesity Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2020 Type: Article Affiliation country: China

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