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Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5.
Kongsomboonvech, Angel K; Rodriguez, Felipe; Diep, Anh L; Justice, Brandon M; Castallanos, Brayan E; Camejo, Ana; Mukhopadhyay, Debanjan; Taylor, Gregory A; Yamamoto, Masahiro; Saeij, Jeroen P J; Reese, Michael L; Jensen, Kirk D C.
Affiliation
  • Kongsomboonvech AK; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.
  • Rodriguez F; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.
  • Diep AL; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.
  • Justice BM; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.
  • Castallanos BE; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.
  • Camejo A; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
  • Mukhopadhyay D; Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, California, United States of America.
  • Taylor GA; Departments of Medicine; Molecular Genetics and Microbiology; and Immunology; and Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina, United States of America.
  • Yamamoto M; Geriatric Research, Education, and Clinical Center, Durham VA Health Care System, Durham, North Carolina, United States of America.
  • Saeij JPJ; Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
  • Reese ML; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.
  • Jensen KDC; Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, California, United States of America.
PLoS Pathog ; 16(8): e1008327, 2020 08.
Article in En | MEDLINE | ID: mdl-32853276
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Toxoplasma / Signal Transduction / Protozoan Proteins / Toxoplasmosis, Animal / Interferon-gamma / CD8-Positive T-Lymphocytes / Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein Limits: Animals Language: En Journal: PLoS Pathog Year: 2020 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Toxoplasma / Signal Transduction / Protozoan Proteins / Toxoplasmosis, Animal / Interferon-gamma / CD8-Positive T-Lymphocytes / Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein Limits: Animals Language: En Journal: PLoS Pathog Year: 2020 Type: Article Affiliation country: United States