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Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix.
Iuliano, James N; Collado, Jinnette Tolentino; Gil, Agnieszka A; Ravindran, Pavithran T; Lukacs, Andras; Shin, SeungYoun; Woroniecka, Helena A; Adamczyk, Katrin; Aramini, James M; Edupuganti, Uthama R; Hall, Christopher R; Greetham, Gregory M; Sazanovich, Igor V; Clark, Ian P; Daryaee, Taraneh; Toettcher, Jared E; French, Jarrod B; Gardner, Kevin H; Simmerling, Carlos L; Meech, Stephen R; Tonge, Peter J.
Affiliation
  • Iuliano JN; Department of Chemistry, Stony Brook University, New York, 11794, United States.
  • Collado JT; Department of Chemistry, Stony Brook University, New York, 11794, United States.
  • Gil AA; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, United States.
  • Ravindran PT; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, United States.
  • Lukacs A; School of Chemistry, University of East Anglia, Norwich, NR4 7TJ, United Kingdom.
  • Shin S; Department of Biophysics, Medical School, University of Pecs, Szigeti út 12, 7624 Pecs, Hungary.
  • Woroniecka HA; Department of Chemistry, Stony Brook University, New York, 11794, United States.
  • Adamczyk K; Department of Chemistry, Stony Brook University, New York, 11794, United States.
  • Aramini JM; School of Chemistry, University of East Anglia, Norwich, NR4 7TJ, United Kingdom.
  • Edupuganti UR; Structural Biology Initiative, CUNY Advanced Science Research Center, 85 St. Nicholas Terrace, New York, New York 10031, United States.
  • Hall CR; Structural Biology Initiative, CUNY Advanced Science Research Center, 85 St. Nicholas Terrace, New York, New York 10031, United States.
  • Greetham GM; Ph.D. Program in Biochemistry, CUNY Graduate Center, New York, New York, United States.
  • Sazanovich IV; School of Chemistry, University of East Anglia, Norwich, NR4 7TJ, United Kingdom.
  • Clark IP; Central Laser Facility, Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot, OX11 0QX, United Kingdom.
  • Daryaee T; Central Laser Facility, Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot, OX11 0QX, United Kingdom.
  • Toettcher JE; Central Laser Facility, Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot, OX11 0QX, United Kingdom.
  • French JB; Department of Chemistry, Stony Brook University, New York, 11794, United States.
  • Gardner KH; Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, United States.
  • Simmerling CL; Department of Chemistry, Stony Brook University, New York, 11794, United States.
  • Meech SR; Hormel Institute, University of Minnesota, Austin, Minnesota 55912, United States.
  • Tonge PJ; Structural Biology Initiative, CUNY Advanced Science Research Center, 85 St. Nicholas Terrace, New York, New York 10031, United States.
ACS Chem Biol ; 15(10): 2752-2765, 2020 10 16.
Article in En | MEDLINE | ID: mdl-32880430

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Avena / Phototropins / Protein Unfolding / Glutamine Language: En Journal: ACS Chem Biol Year: 2020 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Avena / Phototropins / Protein Unfolding / Glutamine Language: En Journal: ACS Chem Biol Year: 2020 Type: Article Affiliation country: United States