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Proteolytic cleavage of Podocin by Matriptase exacerbates podocyte injury.
Ozawa, Shota; Matsubayashi, Masaya; Nanaura, Hitoki; Yanagita, Motoko; Mori, Kiyoshi; Asanuma, Katsuhiko; Kajiwara, Nobuyuki; Hayashi, Kazuyuki; Ohashi, Hiroshi; Kasahara, Masato; Yokoi, Hideki; Kataoka, Hiroaki; Mori, Eiichiro; Nakagawa, Takahiko.
Affiliation
  • Ozawa S; TMK Project at the Medical Innovation Center, Kyoto University, Kyoto, Japan; Research Unit/Innovative Medical Science, Mitsubishi Tanabe Pharma Corporation, Saitama, Japan.
  • Matsubayashi M; Department of Future Basic Medicine, Nara Medical University, Kashihara, Nara, Japan.
  • Nanaura H; Department of Future Basic Medicine, Nara Medical University, Kashihara, Nara, Japan.
  • Yanagita M; TMK Project at the Medical Innovation Center, Kyoto University, Kyoto, Japan; Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan; Institute for the Advanced Study of Human Biology, Kyoto University, Kyoto, Japan.
  • Mori K; TMK Project at the Medical Innovation Center, Kyoto University, Kyoto, Japan; Department of Molecular and Clinical Pharmacology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
  • Asanuma K; TMK Project at the Medical Innovation Center, Kyoto University, Kyoto, Japan; Department of Nephrology, Chiba University, Chiba, Japan.
  • Kajiwara N; Department of Nephrology, Ikeda City Hospital, Ikeda, Osaka, Japan.
  • Hayashi K; Department of Nephrology, Ikeda City Hospital, Ikeda, Osaka, Japan.
  • Ohashi H; Department of Pathology, Ikeda City Hospital, Ikeda, Osaka, Japan.
  • Kasahara M; Institute for Clinical and Translational Science, Nara Medical University, Kashihara, Nara, Japan.
  • Yokoi H; Department of Nephrology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Kataoka H; Department of Pathology, University of Miyazaki, Kihara, Miyazaki, Japan.
  • Mori E; Department of Future Basic Medicine, Nara Medical University, Kashihara, Nara, Japan. Electronic address: emori@naramed-u.ac.jp.
  • Nakagawa T; TMK Project at the Medical Innovation Center, Kyoto University, Kyoto, Japan; Department of Future Basic Medicine, Nara Medical University, Kashihara, Nara, Japan. Electronic address: nakagawt@gmail.com.
J Biol Chem ; 295(47): 16002-16012, 2020 11 20.
Article in En | MEDLINE | ID: mdl-32907879
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine Endopeptidases / Intracellular Signaling Peptides and Proteins / Podocytes / Renal Insufficiency, Chronic / Proteolysis / Membrane Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2020 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine Endopeptidases / Intracellular Signaling Peptides and Proteins / Podocytes / Renal Insufficiency, Chronic / Proteolysis / Membrane Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2020 Type: Article Affiliation country: Japan