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Correction of microtubule defects within Aß plaque-associated dystrophic axons results in lowered Aß release and plaque deposition.
Yao, Yuemang; Nzou, Goodwell; Alle, Thibault; Tsering, Wangchen; Maimaiti, Shaniya; Trojanowski, John Q; Lee, Virginia M-Y; Ballatore, Carlo; Brunden, Kurt R.
Affiliation
  • Yao Y; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Nzou G; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Alle T; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, USA.
  • Tsering W; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Maimaiti S; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Trojanowski JQ; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Lee VM; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Ballatore C; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, USA.
  • Brunden KR; Center for Neurodegenerative Disease Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Alzheimers Dement ; 16(10): 1345-1357, 2020 10.
Article in En | MEDLINE | ID: mdl-32918367
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Triazoles / Brain / Plaque, Amyloid / Hydrocarbons, Halogenated / Microtubules Type of study: Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Journal: Alzheimers Dement Year: 2020 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Triazoles / Brain / Plaque, Amyloid / Hydrocarbons, Halogenated / Microtubules Type of study: Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Journal: Alzheimers Dement Year: 2020 Type: Article Affiliation country: United States