Assessing the dilution effect of specimen pooling on the sensitivity of SARS-CoV-2 PCR tests.

Bateman, Allen C; Mueller, Shanna; Guenther, Kyley; Shult, Peter

Bateman, Allen C; Mueller, Shanna; Guenther, Kyley; Shult, Peter.

Affiliation

Bateman AC; Communicable Disease Division, Wisconsin State Laboratory of Hygiene, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Mueller S; Communicable Disease Division, Wisconsin State Laboratory of Hygiene, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Guenther K; Communicable Disease Division, Wisconsin State Laboratory of Hygiene, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Shult P; Communicable Disease Division, Wisconsin State Laboratory of Hygiene, University of Wisconsin-Madison, Madison, Wisconsin, USA.

J Med Virol ; 93(3): 1568-1572, 2021 03.

Article in En | MEDLINE | ID: mdl-32936471

Subject(s)

COVID-19 Testing/methods; COVID-19/diagnosis; Polymerase Chain Reaction/methods; SARS-CoV-2/genetics; COVID-19/virology; Diagnostic Tests, Routine/methods; Humans; Pandemics/prevention & control; RNA, Viral/genetics; Sensitivity and Specificity; Specimen Handling/methods

Key words

SARS-CoV-2; dilution; pooling; sensitivity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymerase Chain Reaction / COVID-19 Testing / SARS-CoV-2 / COVID-19 Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: J Med Virol Year: 2021 Type: Article Affiliation country: United States

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