Phenotypic Switching of Atherosclerotic Smooth Muscle Cells is Regulated by Activated PARP1-Dependent TET1 Expression.

Zhang, Chao; Chen, Xin; Wang, Ju-Kun; Li, Yu; Cui, Shi-Jun; Wang, Zhonggao; Luo, Tao

Phenotypic Switching of Atherosclerotic Smooth Muscle Cells is Regulated by Activated PARP1-Dependent TET1 Expression.

Zhang, Chao; Chen, Xin; Wang, Ju-Kun; Li, Yu; Cui, Shi-Jun; Wang, Zhonggao; Luo, Tao.

Affiliation

Zhang C; Department of General Surgery, Xuanwu Hospital, Capital Medical University.
Chen X; Department of General Surgery, Xuanwu Hospital, Capital Medical University.
Wang JK; Department of General Surgery, Xuanwu Hospital, Capital Medical University.
Li Y; Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University.
Cui SJ; Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University.
Wang Z; Department of General Surgery, Xuanwu Hospital, Capital Medical University.
Luo T; Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University.

J Atheroscler Thromb ; 28(7): 716-729, 2021 Jul 01.

Article in En | MEDLINE | ID: mdl-32981917

Subject(s)

Atherosclerosis; Mixed Function Oxygenases; Muscle, Smooth, Vascular; Poly (ADP-Ribose) Polymerase-1; Proto-Oncogene Proteins; Vascular Calcification; Atherosclerosis/metabolism; Atherosclerosis/physiopathology; Atherosclerosis/prevention & control; Cell Plasticity; Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; Drug Discovery; Humans; Mixed Function Oxygenases/antagonists & inhibitors; Mixed Function Oxygenases/metabolism; Muscle, Smooth, Vascular/drug effects; Muscle, Smooth, Vascular/metabolism; Muscle, Smooth, Vascular/pathology; Poly (ADP-Ribose) Polymerase-1/antagonists & inhibitors; Poly (ADP-Ribose) Polymerase-1/metabolism; Proto-Oncogene Proteins/antagonists & inhibitors; Proto-Oncogene Proteins/metabolism; Signal Transduction/drug effects; Vascular Calcification/drug therapy; Vascular Calcification/metabolism; Vascular Calcification/physiopathology

Key words

Atherosclerosis; Phenotypic switching; Poly (ADP-ribose) polymerase 1; Teneleven translocation enzyme 1; Vascular smooth muscle cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins / Atherosclerosis / Vascular Calcification / Poly (ADP-Ribose) Polymerase-1 / Mixed Function Oxygenases / Muscle, Smooth, Vascular Limits: Humans Language: En Journal: J Atheroscler Thromb Journal subject: ANGIOLOGIA Year: 2021 Type: Article

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