Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: <i>Post Hoc</i> Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.

Levin, Adeera; Perkovic, Vlado; Wheeler, David C; Hantel, Stefan; George, Jyothis T; von Eynatten, Maximilian; Koitka-Weber, Audrey; Wanner, Christoph

Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.

Levin, Adeera; Perkovic, Vlado; Wheeler, David C; Hantel, Stefan; George, Jyothis T; von Eynatten, Maximilian; Koitka-Weber, Audrey; Wanner, Christoph.

Affiliation

Levin A; Division of Nephrology, University of British Columbia, Vancouver, Canada.
Perkovic V; The George Institute for Global Health, University of New South Wales, Sydney, Australia.
Wheeler DC; The George Institute for Global Health, University of New South Wales, Sydney, Australia.
Hantel S; Centre for Nephrology, University College London, London, United Kingdom.
George JT; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
von Eynatten M; Boehringer Ingelheim International GmbH, Ingelheim, Germany.
Koitka-Weber A; Boehringer Ingelheim International GmbH, Ingelheim, Germany.
Wanner C; Boehringer Ingelheim International GmbH, Ingelheim, Germany.

Clin J Am Soc Nephrol ; 15(10): 1433-1444, 2020 10 07.

Article in En | MEDLINE | ID: mdl-32994159

Subject(s)

Benzhydryl Compounds/therapeutic use; Cardiovascular Diseases/complications; Diabetes Mellitus, Type 2/drug therapy; Glucosides/therapeutic use; Renal Insufficiency, Chronic/classification; Renal Insufficiency, Chronic/physiopathology; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use; Adams-Stokes Syndrome/etiology; Aged; Albuminuria/urine; Benzhydryl Compounds/adverse effects; Creatinine/urine; Diabetes Mellitus, Type 2/complications; Double-Blind Method; Female; Genital Diseases, Female/chemically induced; Genital Diseases, Male/chemically induced; Glomerular Filtration Rate; Glucosides/adverse effects; Heart Failure/etiology; Hospitalization; Humans; Infections/chemically induced; Male; Middle Aged; Mortality; Myocardial Infarction/etiology; Placebos; Renal Insufficiency, Chronic/complications; Sodium-Glucose Transporter 2 Inhibitors/adverse effects

Key words

KDIGO; SGLT2 inhibition; diabetic nephropathy; empagliflozin; glomerular filtration rate; kidney disease

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzhydryl Compounds / Cardiovascular Diseases / Diabetes Mellitus, Type 2 / Renal Insufficiency, Chronic / Sodium-Glucose Transporter 2 Inhibitors / Glucosides Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin J Am Soc Nephrol Journal subject: NEFROLOGIA Year: 2020 Type: Article Affiliation country: Canada

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