Advantages in Wound Healing Process in Female Mice Require Upregulation A<sub>2A</sub>-Mediated Angiogenesis under the Stimulation of 17ß-Estradiol.

Troncoso, Felipe; Herlitz, Kurt; Acurio, Jesenia; Aguayo, Claudio; Guevara, Katherine; Castro, Fidel Ovidio; Godoy, Alejandro S; San Martin, Sebastian; Escudero, Carlos

Advantages in Wound Healing Process in Female Mice Require Upregulation A_2A-Mediated Angiogenesis under the Stimulation of 17ß-Estradiol.

Troncoso, Felipe; Herlitz, Kurt; Acurio, Jesenia; Aguayo, Claudio; Guevara, Katherine; Castro, Fidel Ovidio; Godoy, Alejandro S; San Martin, Sebastian; Escudero, Carlos.

Affiliation

Troncoso F; Vascular Physiology Laboratory, Department of Basic Sciences, Universidad del Bío-Bío, 3780000 Chillán, Chile.
Herlitz K; Programa de Doctorado en Ciencias Veterinarias, Universidad de Concepción, 3780000 Chillán, Chile.
Acurio J; Vascular Physiology Laboratory, Department of Basic Sciences, Universidad del Bío-Bío, 3780000 Chillán, Chile.
Aguayo C; Vascular Physiology Laboratory, Department of Basic Sciences, Universidad del Bío-Bío, 3780000 Chillán, Chile.
Guevara K; Group of Research and Innovation in Vascular Health (GRIVAS Health), 3780000 Chillán, Chile.
Castro FO; Group of Research and Innovation in Vascular Health (GRIVAS Health), 3780000 Chillán, Chile.
Godoy AS; Department of Clinical Biochemistry and Immunology, Faculty of Pharmacy, University of Concepción, 4030000 Concepción, Chile.
San Martin S; Vascular Physiology Laboratory, Department of Basic Sciences, Universidad del Bío-Bío, 3780000 Chillán, Chile.
Escudero C; Department of Animal Science, Faculty of Veterinary Sciences, Universidad de Concepcion, 3780000 Chillán, Chile.

Int J Mol Sci ; 21(19)2020 Sep 28.

Article in En | MEDLINE | ID: mdl-32998232

Subject(s)

Estradiol/pharmacology; Estrogen Receptor alpha/genetics; Estrogen Receptor beta/genetics; Neovascularization, Physiologic/drug effects; Receptor, Adenosine A2A/genetics; Wounds, Penetrating/genetics; Adenosine/analogs & derivatives; Adenosine/pharmacology; Animals; Cell Proliferation/drug effects; Endothelial Cells/cytology; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Estrogen Receptor alpha/antagonists & inhibitors; Estrogen Receptor alpha/metabolism; Estrogen Receptor beta/antagonists & inhibitors; Estrogen Receptor beta/metabolism; Female; Gene Expression Regulation; Lung/cytology; Lung/metabolism; Male; Mice; Mice, Knockout; Neovascularization, Physiologic/genetics; Phenethylamines/pharmacology; Pyrazoles/pharmacology; Pyrimidines/pharmacology; Receptor Cross-Talk; Receptor, Adenosine A2A/metabolism; Sex Factors; Signal Transduction; Wound Healing/drug effects; Wound Healing/genetics; Wounds, Penetrating/drug therapy; Wounds, Penetrating/metabolism; Wounds, Penetrating/pathology

Key words

A2A receptor; adenosine; angiogenesis; wound healing

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Wounds, Penetrating / Neovascularization, Physiologic / Receptor, Adenosine A2A / Estrogen Receptor alpha / Estrogen Receptor beta / Estradiol Language: En Journal: Int J Mol Sci Year: 2020 Type: Article Affiliation country: Chile

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