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Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.
Petri, László; Ábrányi-Balogh, Péter; Tímea, Imre; Pálfy, Gyula; Perczel, András; Knez, Damijan; Hrast, Martina; Gobec, Martina; Sosic, Izidor; Nyíri, Kinga; Vértessy, Beáta G; Jänsch, Niklas; Desczyk, Charlotte; Meyer-Almes, Franz-Josef; Ogris, Iza; Golic Grdadolnik, Simona; Iacovino, Luca Giacinto; Binda, Claudia; Gobec, Stanislav; Keseru, György M.
Affiliation
  • Petri L; Medicinal Chemistry Research Group, Research Centre for Natural Sciences, Magyar tudósok krt 2, 1117, Budapest, Hungary.
  • Ábrányi-Balogh P; Medicinal Chemistry Research Group, Research Centre for Natural Sciences, Magyar tudósok krt 2, 1117, Budapest, Hungary.
  • Tímea I; MS Metabolomics Research Group, Research Centre for Natural Sciences, Magyar tudósok krt 2, 1117, Budapest, Hungary.
  • Pálfy G; Laboratory of Structural Chemistry and Biology &, MTA-ELTE Protein Modelling Research Group, Eötvös Loránd University, Pázmány Péter sétány 1/A, 1117, Budapest, Hungary.
  • Perczel A; Laboratory of Structural Chemistry and Biology &, MTA-ELTE Protein Modelling Research Group, Eötvös Loránd University, Pázmány Péter sétány 1/A, 1117, Budapest, Hungary.
  • Knez D; Faculty of Pharmacy, University of Ljubljana, Askerceva 7, 1000, Ljubljana, Slovenia.
  • Hrast M; Faculty of Pharmacy, University of Ljubljana, Askerceva 7, 1000, Ljubljana, Slovenia.
  • Gobec M; Faculty of Pharmacy, University of Ljubljana, Askerceva 7, 1000, Ljubljana, Slovenia.
  • Sosic I; Faculty of Pharmacy, University of Ljubljana, Askerceva 7, 1000, Ljubljana, Slovenia.
  • Nyíri K; Genome Metabolism Research Group, Research Centre for Natural Sciences, Magyar tudósok krt 2, 1117, Budapest, Hungary.
  • Vértessy BG; Genome Metabolism Research Group, Research Centre for Natural Sciences, Magyar tudósok krt 2, 1117, Budapest, Hungary.
  • Jänsch N; Department of Applied Biotechnology, Budapest University of Technology and Economics, Szt Gellért tér 4, 1111, Budapest, Hungary.
  • Desczyk C; Department of Chemical Engineering and Biotechnology, University of Applied Sciences Darmstadt, Schnittspahnstraße 12, 64287, Darmstadt, Germany.
  • Meyer-Almes FJ; Department of Chemical Engineering and Biotechnology, University of Applied Sciences Darmstadt, Schnittspahnstraße 12, 64287, Darmstadt, Germany.
  • Ogris I; Department of Chemical Engineering and Biotechnology, University of Applied Sciences Darmstadt, Schnittspahnstraße 12, 64287, Darmstadt, Germany.
  • Golic Grdadolnik S; Laboratory for Molecular Structural Dynamics, National Institute of Chemistry, Hajdrihova 19, 1000, Ljubljana, Slovenia.
  • Iacovino LG; Laboratory for Molecular Structural Dynamics, National Institute of Chemistry, Hajdrihova 19, 1000, Ljubljana, Slovenia.
  • Binda C; Department of Biology and Biotechnology, University of Pavia, via Ferrata 1, 27100, Pavia, Italy.
  • Gobec S; Department of Biology and Biotechnology, University of Pavia, via Ferrata 1, 27100, Pavia, Italy.
  • Keseru GM; Faculty of Pharmacy, University of Ljubljana, Askerceva 7, 1000, Ljubljana, Slovenia.
Chembiochem ; 22(4): 743-753, 2021 02 15.
Article in En | MEDLINE | ID: mdl-33030752
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alkyl and Aryl Transferases / Proteome / Cysteine / Enzyme Inhibitors / Drug Discovery Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2021 Type: Article Affiliation country: Hungary
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alkyl and Aryl Transferases / Proteome / Cysteine / Enzyme Inhibitors / Drug Discovery Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2021 Type: Article Affiliation country: Hungary