Burden of Parkinson's Disease by Severity: Health Care Costs in the U.S. Medicare Population.
Mov Disord
; 36(1): 133-142, 2021 01.
Article
in En
| MEDLINE
| ID: mdl-33031604
ABSTRACT
BACKGROUND:
Current understanding of the health care costs of Parkinson's disease (PD) and the incremental burden of advanced disease is incomplete.OBJECTIVES:
The aim of this study was to assess the direct economic burden associated with advanced versus mild/moderate PD in a prevalent national sample of elderly U.S. Medicare beneficiaries with a PD diagnosis.METHODS:
Analyzing 100% fee-for-service Medicare claims from 2013, we defined advanced PD with a medication-based algorithm and calculated all-cause and PD-related costs for the overall sample and by disease severity. We measured primary PD-related costs (based on claims with a primary diagnosis of PD) and any PD-related costs (based on claims with PD in any diagnostic field). Generalized linear models were used to estimate risk-adjusted mean cost differences between the advanced and mild/moderate PD groups for the calendar year.RESULTS:
The final sample (N = 144,703) had mean observed all-cause, primary PD-related, and any PD-related costs of $23,041 (SD, $34,045), $3429 (SD, $7431), and $9924 (SD, $22,140), respectively. Twenty percent of patients were classified as advanced PD. Costs varied substantially; any PD-related mean costs were $483 for the lowest patient decile (which included 1% of the advanced group) and $48,145 for the highest decile (which included 15% of the advanced group). Incremental risk-adjusted costs of advanced PD were $5818 (95% confidence interval [CI] $5411-$6225) for all-cause costs, $3644 (95% CI $3484-$3806) for primary PD-related costs, and $6088 (95% CI $5779-$6398) for any PD-related costs.CONCLUSIONS:
Elderly Medicare beneficiaries with PD had substantial variation in PD-related costs. Advanced PD was associated with a larger economic burden than mild/moderate PD. © 2020 International Parkinson and Movement Disorder Society.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parkinson Disease
Type of study:
Health_economic_evaluation
/
Observational_studies
/
Risk_factors_studies
Limits:
Aged
/
Humans
Country/Region as subject:
America do norte
Language:
En
Journal:
Mov Disord
Journal subject:
NEUROLOGIA
Year:
2021
Type:
Article
Affiliation country:
United States