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SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses.
Banerjee, Abhik K; Blanco, Mario R; Bruce, Emily A; Honson, Drew D; Chen, Linlin M; Chow, Amy; Bhat, Prashant; Ollikainen, Noah; Quinodoz, Sofia A; Loney, Colin; Thai, Jasmine; Miller, Zachary D; Lin, Aaron E; Schmidt, Madaline M; Stewart, Douglas G; Goldfarb, Daniel; De Lorenzo, Giuditta; Rihn, Suzannah J; Voorhees, Rebecca M; Botten, Jason W; Majumdar, Devdoot; Guttman, Mitchell.
Affiliation
  • Banerjee AK; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
  • Blanco MR; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Bruce EA; Departments of Medicine, Division of Immunobiology and Microbiology, and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.
  • Honson DD; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Chen LM; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Chow A; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Bhat P; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Ollikainen N; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Quinodoz SA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Loney C; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow G61 1QH, UK.
  • Thai J; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Miller ZD; Department of Surgery and University of Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT 05405, USA.
  • Lin AE; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Schmidt MM; Departments of Medicine, Division of Immunobiology and Microbiology, and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.
  • Stewart DG; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow G61 1QH, UK.
  • Goldfarb D; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow G61 1QH, UK.
  • De Lorenzo G; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow G61 1QH, UK.
  • Rihn SJ; MRC-University of Glasgow Centre for Virus Research (CVR), Glasgow G61 1QH, UK.
  • Voorhees RM; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Botten JW; Departments of Medicine, Division of Immunobiology and Microbiology, and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, VT 05405, USA.
  • Majumdar D; Department of Surgery and University of Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: dev.Majumdar@med.uvm.edu.
  • Guttman M; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: mguttman@caltech.edu.
Cell ; 183(5): 1325-1339.e21, 2020 11 25.
Article in En | MEDLINE | ID: mdl-33080218
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / RNA Splicing / Viral Nonstructural Proteins / Host-Pathogen Interactions / SARS-CoV-2 / COVID-19 Limits: Animals / Humans Language: En Journal: Cell Year: 2020 Type: Article Affiliation country: United States
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / RNA Splicing / Viral Nonstructural Proteins / Host-Pathogen Interactions / SARS-CoV-2 / COVID-19 Limits: Animals / Humans Language: En Journal: Cell Year: 2020 Type: Article Affiliation country: United States