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Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos.
Zuccaro, Michael V; Xu, Jia; Mitchell, Carl; Marin, Diego; Zimmerman, Raymond; Rana, Bhavini; Weinstein, Everett; King, Rebeca T; Palmerola, Katherine L; Smith, Morgan E; Tsang, Stephen H; Goland, Robin; Jasin, Maria; Lobo, Rogerio; Treff, Nathan; Egli, Dieter.
Affiliation
  • Zuccaro MV; Department of Pediatrics and Naomi Berrie Diabetes Center, Columbia University, New York, NY 10032, USA; Columbia University Stem Cell Initiative, New York, NY 10032, USA.
  • Xu J; Genomic Prediction Inc., North Brunswick, NJ 08902, USA.
  • Mitchell C; Columbia University Stem Cell Initiative, New York, NY 10032, USA.
  • Marin D; Genomic Prediction Inc., North Brunswick, NJ 08902, USA.
  • Zimmerman R; Genomic Prediction Inc., North Brunswick, NJ 08902, USA.
  • Rana B; Genomic Prediction Inc., North Brunswick, NJ 08902, USA; Department of Molecular Biosciences, Rutgers, The State University of New Jersey, New Brunswick, NJ 08854, USA.
  • Weinstein E; Department of Pediatrics and Naomi Berrie Diabetes Center, Columbia University, New York, NY 10032, USA.
  • King RT; Department of Pediatrics and Naomi Berrie Diabetes Center, Columbia University, New York, NY 10032, USA.
  • Palmerola KL; Department of Obstetrics and Gynecology, Columbia University, New York, NY 10032, USA.
  • Smith ME; Department of Pediatrics and Naomi Berrie Diabetes Center, Columbia University, New York, NY 10032, USA.
  • Tsang SH; Columbia University Stem Cell Initiative, New York, NY 10032, USA; Departments of Ophthalmology, Pathology & Cell Biology, Columbia University. New York, NY, 10032, USA.
  • Goland R; Department of Pediatrics and Naomi Berrie Diabetes Center, Columbia University, New York, NY 10032, USA.
  • Jasin M; Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Lobo R; Department of Obstetrics and Gynecology, Columbia University, New York, NY 10032, USA.
  • Treff N; Genomic Prediction Inc., North Brunswick, NJ 08902, USA; Department of Molecular Biosciences, Rutgers, The State University of New Jersey, New Brunswick, NJ 08854, USA.
  • Egli D; Department of Pediatrics and Naomi Berrie Diabetes Center, Columbia University, New York, NY 10032, USA; Columbia University Stem Cell Initiative, New York, NY 10032, USA; Department of Obstetrics and Gynecology, Columbia University, New York, NY 10032, USA. Electronic address: de2220@cumc.columbia.
Cell ; 183(6): 1650-1664.e15, 2020 12 10.
Article in En | MEDLINE | ID: mdl-33125898
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes, Human / Embryo, Mammalian / Alleles / CRISPR-Associated Protein 9 Limits: Animals / Humans Language: En Journal: Cell Year: 2020 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes, Human / Embryo, Mammalian / Alleles / CRISPR-Associated Protein 9 Limits: Animals / Humans Language: En Journal: Cell Year: 2020 Type: Article Affiliation country: United States