An antibody-free dual-biomarker rapid enrichment workflow (AnDREW) improves the sensitivity of malaria rapid diagnostic tests.

Kantor, Andrew G; Markwalter, Christine F; Nourani, Armin; Wright, David W

Kantor, Andrew G; Markwalter, Christine F; Nourani, Armin; Wright, David W.

Affiliation

Kantor AG; Department of Chemistry, Vanderbilt University, Nashville, TN, 37235, USA.
Markwalter CF; Department of Chemistry, Vanderbilt University, Nashville, TN, 37235, USA.
Nourani A; Department of Chemistry, Vanderbilt University, Nashville, TN, 37235, USA.
Wright DW; Department of Chemistry, Vanderbilt University, Nashville, TN, 37235, USA. Electronic address: david.wright@vanderbilt.edu.

Anal Biochem ; 612: 114020, 2021 01 01.

Article in En | MEDLINE | ID: mdl-33207186

Subject(s)

Antigens, Protozoan/analysis; Diagnostic Tests, Routine/methods; Malaria/diagnosis; Reagent Kits, Diagnostic/parasitology; Aptamers, Nucleotide/chemistry; Biomarkers/analysis; Humans; Kinetics; L-Lactate Dehydrogenase/analysis; Limit of Detection; Magnetite Nanoparticles/chemistry; Malaria/blood; Nitrilotriacetic Acid/chemistry; Plasmodium falciparum/chemistry; Plasmodium vivax/chemistry; Protein Binding; Protozoan Proteins/analysis; Sensitivity and Specificity; Zinc/chemistry

Key words

Aptamer; Immobilized metal affinity chromatography (IMAC); Malaria; Plasmodium vivax; Rapid diagnostic test (RDT)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reagent Kits, Diagnostic / Diagnostic Tests, Routine / Malaria / Antigens, Protozoan Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Anal Biochem Year: 2021 Type: Article Affiliation country: United States

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