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Phase 2 study of the safety and efficacy of umbralisib in patients with CLL who are intolerant to BTK or PI3Kδ inhibitor therapy.
Mato, Anthony R; Ghosh, Nilanjan; Schuster, Stephen J; Lamanna, Nicole; Pagel, John M; Flinn, Ian W; Barrientos, Jacqueline C; Rai, Kanti R; Reeves, James A; Cheson, Bruce D; Barr, Paul M; Kambhampati, Suman; Lansigan, Frederick; Pu, Jeffrey J; Skarbnik, Alan P; Roeker, Lindsey; Fonseca, Gustavo A; Sitlinger, Andrea; Hamadeh, Issam S; Dorsey, Colleen; LaRatta, Nicole; Weissbrot, Hanna; Luning Prak, Eline T; Tsao, Patricia; Paskalis, Dana; Sportelli, Peter; Miskin, Hari P; Weiss, Michael S; Svoboda, Jakub; Brander, Danielle M.
Affiliation
  • Mato AR; University of Pennsylvania Cancer Center, Philadelphia, PA.
  • Ghosh N; Atrium Health, Charlotte, NC.
  • Schuster SJ; University of Pennsylvania Cancer Center, Philadelphia, PA.
  • Lamanna N; New York-Presbyterian Columbia University Medical Center, New York, NY.
  • Pagel JM; Swedish Cancer Institute, Seattle, WA.
  • Flinn IW; Tennessee Oncology/Sarah Cannon Research Institute, Nashville, TN.
  • Barrientos JC; Northwell Health/CLL Research and Treatment Program, New Hyde Park, NY.
  • Rai KR; Northwell Health/CLL Research and Treatment Program, New Hyde Park, NY.
  • Reeves JA; Florida Cancer Specialists/Sarah Cannon Research Institute, Fort Myers, FL.
  • Cheson BD; Georgetown University Hospital Lombardi Comprehensive Cancer Center, Washington, DC.
  • Barr PM; Wilmot Cancer Institute, University of Rochester, Rochester, NY.
  • Kambhampati S; Sarah Cannon Research Institute at Research Medical Center, Kansas City, KS.
  • Lansigan F; Dartmouth-Hitchcock Medical Center, Lebanon, NH.
  • Pu JJ; Upstate Cancer Center, Syracuse, NY.
  • Skarbnik AP; John Theurer Cancer Center, Hackensack, NJ.
  • Roeker L; Memorial Sloan Kettering Cancer Center, New York, NY.
  • Fonseca GA; Florida Cancer Specialists/Sarah Cannon Research Institute, St. Petersburg, FL.
  • Sitlinger A; Duke University Medical Center, Durham, NC.
  • Hamadeh IS; Levine Cancer Institute, Gainesville, FL; and.
  • Dorsey C; Memorial Sloan Kettering Cancer Center, New York, NY.
  • LaRatta N; University of Pennsylvania Cancer Center, Philadelphia, PA.
  • Weissbrot H; University of Pennsylvania Cancer Center, Philadelphia, PA.
  • Luning Prak ET; University of Pennsylvania Cancer Center, Philadelphia, PA.
  • Tsao P; University of Pennsylvania Cancer Center, Philadelphia, PA.
  • Paskalis D; TG Therapeutics, Inc., New York, NY.
  • Sportelli P; TG Therapeutics, Inc., New York, NY.
  • Miskin HP; TG Therapeutics, Inc., New York, NY.
  • Weiss MS; TG Therapeutics, Inc., New York, NY.
  • Svoboda J; University of Pennsylvania Cancer Center, Philadelphia, PA.
  • Brander DM; Duke University Medical Center, Durham, NC.
Blood ; 137(20): 2817-2826, 2021 05 20.
Article in En | MEDLINE | ID: mdl-33259589
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Protein Kinase Inhibitors / Class I Phosphatidylinositol 3-Kinases / Heterocyclic Compounds, 4 or More Rings / Neoplasm Proteins / Antineoplastic Agents Type of study: Clinical_trials / Etiology_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Blood Year: 2021 Type: Article Affiliation country: Panama
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Protein Kinase Inhibitors / Class I Phosphatidylinositol 3-Kinases / Heterocyclic Compounds, 4 or More Rings / Neoplasm Proteins / Antineoplastic Agents Type of study: Clinical_trials / Etiology_studies Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Blood Year: 2021 Type: Article Affiliation country: Panama