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A Phase 1 study of RO6870810, a novel bromodomain and extra-terminal protein inhibitor, in patients with NUT carcinoma, other solid tumours, or diffuse large B-cell lymphoma.
Shapiro, Geoffrey I; LoRusso, Patricia; Dowlati, Afshin; T Do, Khanh; Jacobson, Caron A; Vaishampayan, Ulka; Weise, Amy; Caimi, Paolo F; Eder, Joseph Paul; French, Christopher A; Labriola-Tompkins, Emily; Boisserie, Frédéric; Pierceall, William E; Zhi, Jianguo; Passe, Sharon; DeMario, Mark; Kornacker, Martin; Armand, Philippe.
Affiliation
  • Shapiro GI; Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. geoffrey_shapiro@dfci.harvard.edu.
  • LoRusso P; Early Phase Clinical Trials Program, Yale University Medical Center, New Haven, CT, USA.
  • Dowlati A; Department of Medicine-Hematology and Oncology, University Hospitals Seidman Cancer Center, Cleveland, OH, USA.
  • T Do K; Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Jacobson CA; Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Vaishampayan U; Department of Oncology, Karmanos Cancer Institute, Detroit, MI, USA.
  • Weise A; Medical Oncology, Karmanos Cancer Institute, Detroit, MI, USA.
  • Caimi PF; Department of Medicine-Hematology and Oncology, University Hospitals Seidman Cancer Center, Cleveland, OH, USA.
  • Eder JP; Early Phase Clinical Trials Program, Yale University Medical Center, New Haven, CT, USA.
  • French CA; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Labriola-Tompkins E; Roche Pharma Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Boisserie F; Roche Pharma Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Pierceall WE; Roche Pharma Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Zhi J; Roche Pharma Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Passe S; Roche Pharma Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • DeMario M; Roche Pharma Research and Early Development, Roche Innovation Center New York, New York, NY, USA.
  • Kornacker M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
  • Armand P; Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Br J Cancer ; 124(4): 744-753, 2021 02.
Article in En | MEDLINE | ID: mdl-33311588
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azepines / Nuclear Proteins / Proteins / Lymphoma, Large B-Cell, Diffuse / Neoplasm Proteins / Neoplasms Type of study: Clinical_trials Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Br J Cancer Year: 2021 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azepines / Nuclear Proteins / Proteins / Lymphoma, Large B-Cell, Diffuse / Neoplasm Proteins / Neoplasms Type of study: Clinical_trials Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Br J Cancer Year: 2021 Type: Article Affiliation country: United States