A Dose-finding Study of Metronomic Oral Vinorelbine in Combination With Oral Cyclophosphamide and Bevacizumab in Patients With Advanced Breast Cancer.

Sanna, Giuseppina; Pestrin, Marta; Moretti, Erica; Biagioni, Chiara; De Santo, Irene; Gabellini, Stefano; Galardi, Francesca; McCartney, Amelia; Biganzoli, Laura

Sanna, Giuseppina; Pestrin, Marta; Moretti, Erica; Biagioni, Chiara; De Santo, Irene; Gabellini, Stefano; Galardi, Francesca; McCartney, Amelia; Biganzoli, Laura.

Affiliation

Sanna G; Medical Oncology Department, Nuovo Ospedale-Santo Stefano Instituto Toscano Tumori, Prato, Italy. Electronic address: giuseppina.sanna@uslcentro.toscana.it.
Pestrin M; Oncologia Medica, Azienda Sanitaria Universitaria Giuliano Isontina, Gorizia, Italy.
Moretti E; Medical Oncology Department, Nuovo Ospedale-Santo Stefano Instituto Toscano Tumori, Prato, Italy.
Biagioni C; Bioinformatics Unit, Hospital of Prato, Prato, Italy.
De Santo I; Oncologia Medica, Ospedale Misericordia di Grosseto, Grosseto, Italy.
Gabellini S; Medical Oncology Department, Nuovo Ospedale-Santo Stefano Instituto Toscano Tumori, Prato, Italy.
Galardi F; Sandro Pitigliani Translational Research Unit, Hospital of Prato, Prato, Italy.
McCartney A; Medical Oncology Department, Nuovo Ospedale-Santo Stefano Instituto Toscano Tumori, Prato, Italy.
Biganzoli L; Medical Oncology Department, Nuovo Ospedale-Santo Stefano Instituto Toscano Tumori, Prato, Italy.

Clin Breast Cancer ; 21(4): e332-e339, 2021 08.

Article in En | MEDLINE | ID: mdl-33353853

Subject(s)

Antineoplastic Agents/administration & dosage; Bevacizumab/administration & dosage; Breast Neoplasms/drug therapy; Carcinoma/drug therapy; Cyclophosphamide/administration & dosage; Vinorelbine/administration & dosage; Administration, Metronomic; Administration, Oral; Adult; Aged; Breast Neoplasms/pathology; Carcinoma/pathology; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelial Cells; Female; Humans; Middle Aged; Neoplastic Cells, Circulating; Pilot Projects; Prospective Studies

Key words

Anti-angiogenesis; Circulating endothelial cells; Cyclophosphamide bevacizumab; Metronomic chemotherapy; Oral vinorelbine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Carcinoma / Cyclophosphamide / Bevacizumab / Vinorelbine / Antineoplastic Agents Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Clin Breast Cancer Journal subject: NEOPLASIAS Year: 2021 Type: Article

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