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Tetrahydrophthalazinone Inhibitor of Phosphodiesterase with In Vitro Activity against Intracellular Trypanosomatids.
de Araújo, Julianna Siciliano; Peres, Raiza Brandão; Bernardino da Silva, Patrícia; Batista, Marcos Meuser; Sterk, Geert Jan; Maes, Louis; Caljon, Guy; Leurs, Rob; de Koning, Harry P; Kalejaiye, Titilola D; Soeiro, Maria de Nazaré Correia.
Affiliation
  • de Araújo JS; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
  • Peres RB; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
  • Bernardino da Silva P; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
  • Batista MM; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
  • Sterk GJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Maes L; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
  • Caljon G; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
  • Leurs R; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • de Koning HP; Institute of Infection, Immunity & Inflammation, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Kalejaiye TD; Institute of Infection, Immunity & Inflammation, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Soeiro MNC; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil soeiro@ioc.fiocruz.br.
Antimicrob Agents Chemother ; 65(3)2021 02 17.
Article in En | MEDLINE | ID: mdl-33361300
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanosoma cruzi / Leishmania mexicana / Chagas Disease / Antiprotozoal Agents Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 2021 Type: Article Affiliation country: Brazil
Fulltext
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanosoma cruzi / Leishmania mexicana / Chagas Disease / Antiprotozoal Agents Limits: Humans Language: En Journal: Antimicrob Agents Chemother Year: 2021 Type: Article Affiliation country: Brazil