A single-center retrospective analysis of outcome measures and consolidation strategies for relapsed and refractory primary CNS lymphoma.

Bonm, Alipi V; Gibson, Alec W; Holmberg, Leona A; Mielcarek, Marco; McGranahan, Tresa; Taylor, Lynne P; Graber, Jerome J

Bonm, Alipi V; Gibson, Alec W; Holmberg, Leona A; Mielcarek, Marco; McGranahan, Tresa; Taylor, Lynne P; Graber, Jerome J.

Affiliation

Bonm AV; Department of Neurology, University of Washington, Seattle, WA, USA.
Gibson AW; Medical Scientist Training Program, University of Washington, Seattle, WA, USA.
Holmberg LA; Department of Medicine, University of Washington, Seattle, WA, USA.
Mielcarek M; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
McGranahan T; Department of Medicine, University of Washington, Seattle, WA, USA.
Taylor LP; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Graber JJ; Departments of Neurology and Neurosurgery, Alvord Brain Tumor Center, University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA, 98195, USA.

J Neurooncol ; 151(2): 193-200, 2021 Jan.

Article in En | MEDLINE | ID: mdl-33398532

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Central Nervous System Neoplasms/mortality; Consolidation Chemotherapy/mortality; Hematopoietic Stem Cell Transplantation/mortality; Lymphoma/mortality; Neoplasm Recurrence, Local/mortality; Salvage Therapy; Adult; Aged; Aged, 80 and over; Central Nervous System Neoplasms/pathology; Central Nervous System Neoplasms/therapy; Combined Modality Therapy; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Lymphoma/pathology; Lymphoma/therapy; Male; Middle Aged; Neoplasm Recurrence, Local/pathology; Neoplasm Recurrence, Local/therapy; Prognosis; Retrospective Studies; Survival Rate; Transplantation, Autologous

Key words

Autologous peripheral blood stem cell transplant; Primary CNS lymphoma; Progression-free survival; Recurrent primary CNS lymphoma; Surrogate endpoints

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Salvage Therapy / Central Nervous System Neoplasms / Hematopoietic Stem Cell Transplantation / Consolidation Chemotherapy / Lymphoma / Neoplasm Recurrence, Local Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Neurooncol Year: 2021 Type: Article Affiliation country: United States

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