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Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption.
Gondim, Marcos V P; Sherrill-Mix, Scott; Bibollet-Ruche, Frederic; Russell, Ronnie M; Trimboli, Stephanie; Smith, Andrew G; Li, Yingying; Liu, Weimin; Avitto, Alexa N; DeVoto, Julia C; Connell, Jesse; Fenton-May, Angharad E; Pellegrino, Pierre; Williams, Ian; Papasavvas, Emmanouil; Lorenzi, Julio C C; Salantes, D Brenda; Mampe, Felicity; Monroy, M Alexandra; Cohen, Yehuda Z; Heath, Sonya; Saag, Michael S; Montaner, Luis J; Collman, Ronald G; Siliciano, Janet M; Siliciano, Robert F; Plenderleith, Lindsey J; Sharp, Paul M; Caskey, Marina; Nussenzweig, Michel C; Shaw, George M; Borrow, Persephone; Bar, Katharine J; Hahn, Beatrice H.
Affiliation
  • Gondim MVP; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Sherrill-Mix S; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Bibollet-Ruche F; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Russell RM; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Trimboli S; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Smith AG; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Li Y; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Liu W; University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Avitto AN; WuXi AppTec Inc., Philadelphia, PA 19112, USA.
  • DeVoto JC; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Connell J; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Fenton-May AE; Gene Therapy Program, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Pellegrino P; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA.
  • Williams I; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Papasavvas E; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lorenzi JCC; Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7FZ, UK.
  • Salantes DB; Centre for Clinical Research in Infection and Sexual Health, Institute for Global Health, University College London, London WC1E 6JB, UK.
  • Mampe F; Centre for Clinical Research in Infection and Sexual Health, Institute for Global Health, University College London, London WC1E 6JB, UK.
  • Monroy MA; Vaccine and Immunotherapy Center, Wistar Institute, Philadelphia, PA 19104, USA.
  • Cohen YZ; Laboratory of Molecular Immunology, Rockefeller University, New York, NY 10065, USA.
  • Heath S; Century Therapeutics, Philadelphia, PA 19104, USA.
  • Saag MS; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Montaner LJ; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Collman RG; Sanofi, Bridgewater, NJ 08807, USA.
  • Siliciano JM; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Siliciano RF; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Plenderleith LJ; Vaccine and Immunotherapy Center, Wistar Institute, Philadelphia, PA 19104, USA.
  • Sharp PM; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Caskey M; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Nussenzweig MC; Department of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Shaw GM; Department of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Borrow P; Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Bar KJ; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3FL, UK.
  • Hahn BH; Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh EH9 3FL, UK.
Sci Transl Med ; 13(576)2021 01 13.
Article in En | MEDLINE | ID: mdl-33441429
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / HIV Infections / HIV-1 Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2021 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / HIV Infections / HIV-1 Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2021 Type: Article Affiliation country: United States