Dynamic subcellular localization and transcription activity of the SRF cofactor MKL2 in the striatum are regulated by MAPK.

Ariza, Anthony; Funahashi, Yasuhiro; Kozawa, Sachi; Omar Faruk, Md; Nagai, Taku; Amano, Mutsuki; Kaibuchi, Kozo

Ariza, Anthony; Funahashi, Yasuhiro; Kozawa, Sachi; Omar Faruk, Md; Nagai, Taku; Amano, Mutsuki; Kaibuchi, Kozo.

Affiliation

Ariza A; Department of Cell Pharmacology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
Funahashi Y; Department of Cell Pharmacology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
Kozawa S; Research Project for Neural and Tumor Signaling, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, Japan.
Omar Faruk M; Department of Cell Pharmacology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
Nagai T; Department of Cell Pharmacology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
Amano M; Division of Behavioral Neuropharmacology, Project Office for Neuropsychological Research Center, Fujita Health University, Toyoake, Aichi, Japan.
Kaibuchi K; Department of Cell Pharmacology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

J Neurochem ; 157(6): 1774-1788, 2021 06.

Article in En | MEDLINE | ID: mdl-33449379

Subject(s)

Corpus Striatum/metabolism; Intracellular Space/metabolism; Mitogen-Activated Protein Kinases/metabolism; Serum Response Factor/metabolism; Transcription Factors/metabolism; Transcriptional Activation/physiology; Animals; COS Cells; Chlorocebus aethiops; Cocaine/pharmacology; Corpus Striatum/chemistry; Corpus Striatum/drug effects; Dopamine Uptake Inhibitors/pharmacology; Female; HEK293 Cells; Humans; Intracellular Space/chemistry; Intracellular Space/drug effects; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mitogen-Activated Protein Kinases/analysis; Organ Culture Techniques; Pregnancy; Serum Response Factor/analysis; Transcription Factors/analysis; Transcriptional Activation/drug effects; Xenopus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Transcriptional Activation / Corpus Striatum / Mitogen-Activated Protein Kinases / Serum Response Factor / Intracellular Space Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male / Pregnancy Language: En Journal: J Neurochem Year: 2021 Type: Article Affiliation country: Japan

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