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High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming.
Hu, Guangan; Su, Yang; Kang, Byong Ha; Fan, Zhongqi; Dong, Ting; Brown, Douglas R; Cheah, Jaime; Wittrup, Karl Dane; Chen, Jianzhu.
Affiliation
  • Hu G; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA. gahu@mit.edu.
  • Su Y; Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA. gahu@mit.edu.
  • Kang BH; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
  • Fan Z; Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
  • Dong T; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
  • Brown DR; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
  • Cheah J; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
  • Wittrup KD; Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
  • Chen J; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.
Nat Commun ; 12(1): 773, 2021 02 03.
Article in En | MEDLINE | ID: mdl-33536439
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Products / High-Throughput Screening Assays / Macrophage Activation / Macrophages / Anti-Inflammatory Agents Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Products / High-Throughput Screening Assays / Macrophage Activation / Macrophages / Anti-Inflammatory Agents Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: United States