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Enhancers predominantly regulate gene expression during differentiation via transcription initiation.
Larke, Martin S C; Schwessinger, Ron; Nojima, Takayuki; Telenius, Jelena; Beagrie, Robert A; Downes, Damien J; Oudelaar, A Marieke; Truch, Julia; Graham, Bryony; Bender, M A; Proudfoot, Nicholas J; Higgs, Douglas R; Hughes, Jim R.
Affiliation
  • Larke MSC; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxfor
  • Schwessinger R; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxfor
  • Nojima T; Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.
  • Telenius J; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Beagrie RA; Laboratory of Gene Regulation, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Downes DJ; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Oudelaar AM; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxfor
  • Truch J; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Graham B; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Bender MA; Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Proudfoot NJ; Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.
  • Higgs DR; Laboratory of Gene Regulation, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. Electronic address: doug.higgs@imm.ox.ac.uk.
  • Hughes JR; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxfor
Mol Cell ; 81(5): 983-997.e7, 2021 03 04.
Article in En | MEDLINE | ID: mdl-33539786
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA Polymerase II / Enhancer Elements, Genetic / Promoter Regions, Genetic / Alpha-Globins / Beta-Globins / Transcription Initiation, Genetic Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA Polymerase II / Enhancer Elements, Genetic / Promoter Regions, Genetic / Alpha-Globins / Beta-Globins / Transcription Initiation, Genetic Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article