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A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder.
Gennaccaro, Laura; Fuchs, Claudia; Loi, Manuela; Roncacè, Vincenzo; Trazzi, Stefania; Ait-Bali, Yassine; Galvani, Giuseppe; Berardi, Anna Cecilia; Medici, Giorgio; Tassinari, Marianna; Ren, Elisa; Rimondini, Roberto; Giustetto, Maurizio; Aicardi, Giorgio; Ciani, Elisabetta.
Affiliation
  • Gennaccaro L; Department of Biomedical and Neuromotor Science, University of Bologna, Bologna, Italy.
  • Fuchs C; Department of Biomedical and Neuromotor Science, University of Bologna, Bologna, Italy.
  • Loi M; Department of Biomedical and Neuromotor Science, University of Bologna, Bologna, Italy.
  • Roncacè V; Department for Life Quality Studies, University of Bologna, Bologna, Italy.
  • Trazzi S; Department of Biomedical and Neuromotor Science, University of Bologna, Bologna, Italy.
  • Ait-Bali Y; Department of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy.
  • Galvani G; Department of Biomedical and Neuromotor Science, University of Bologna, Bologna, Italy.
  • Berardi AC; Department for Life Quality Studies, University of Bologna, Bologna, Italy.
  • Medici G; Department of Biomedical and Neuromotor Science, University of Bologna, Bologna, Italy.
  • Tassinari M; Department of Biomedical and Neuromotor Science, University of Bologna, Bologna, Italy.
  • Ren E; Department of Biomedical and Neuromotor Science, University of Bologna, Bologna, Italy.
  • Rimondini R; Department of Medical and Clinical Sciences, University of Bologna, Bologna, Italy.
  • Giustetto M; Department of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy.
  • Aicardi G; Department for Life Quality Studies, University of Bologna, Bologna, Italy. Electronic address: giorgio.aicardi@unibo.it.
  • Ciani E; Department of Biomedical and Neuromotor Science, University of Bologna, Bologna, Italy. Electronic address: elisabetta.ciani@unibo.it.
Neurobiol Dis ; 153: 105304, 2021 06.
Article in En | MEDLINE | ID: mdl-33621640
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spasms, Infantile / Protein Serine-Threonine Kinases / Receptors, GABA-B / Long-Term Potentiation / GABA-B Receptor Antagonists / GABAergic Neurons / Perirhinal Cortex / Epileptic Syndromes Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2021 Type: Article Affiliation country: Italy
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spasms, Infantile / Protein Serine-Threonine Kinases / Receptors, GABA-B / Long-Term Potentiation / GABA-B Receptor Antagonists / GABAergic Neurons / Perirhinal Cortex / Epileptic Syndromes Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2021 Type: Article Affiliation country: Italy