A White Grape Juice Extract Reduces Fat Accumulation through the Modulation of Ghrelin and Leptin Expression in an In Vivo Model of Overfed Zebrafish.

Montalbano, Giuseppe; Maugeri, Alessandro; Guerrera, Maria Cristina; Miceli, Natalizia; Navarra, Michele; Barreca, Davide; Cirmi, Santa; Germanà, Antonino

Montalbano, Giuseppe; Maugeri, Alessandro; Guerrera, Maria Cristina; Miceli, Natalizia; Navarra, Michele; Barreca, Davide; Cirmi, Santa; Germanà, Antonino.

Affiliation

Montalbano G; Zebrafish Neuromorphology Lab, Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy.
Maugeri A; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Guerrera MC; Zebrafish Neuromorphology Lab, Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy.
Miceli N; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Navarra M; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Barreca D; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Cirmi S; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Germanà A; Department of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70125 Bari, Italy.

Molecules ; 26(4)2021 Feb 20.

Article in En | MEDLINE | ID: mdl-33672773

Subject(s)

Adipocytes/drug effects; Fats/antagonists & inhibitors; Ghrelin/antagonists & inhibitors; Leptin/antagonists & inhibitors; Plant Extracts/pharmacology; Vitis/chemistry; Animals; Disease Models, Animal; Fats/metabolism; Fruit and Vegetable Juices/analysis; Ghrelin/genetics; Ghrelin/metabolism; Leptin/genetics; Leptin/metabolism; Molecular Structure; Obesity/drug therapy; Obesity/metabolism; Plant Extracts/administration & dosage; Plant Extracts/chemistry; RNA, Messenger/antagonists & inhibitors; RNA, Messenger/genetics; RNA, Messenger/metabolism; Zebrafish

Key words

Danio rerio; Vitis vinifera; diet-induced obesity; flavonoids; lipolysis; polyphenols; white grape juice; zebrafish

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Adipocytes / Leptin / Vitis / Ghrelin / Fats Limits: Animals Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2021 Type: Article Affiliation country: Italy

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