Prognostic significance of PD-L1-positive cancer-associated fibroblasts in patients with triple-negative breast cancer.

Yoshikawa, Katsuhiro; Ishida, Mitsuaki; Yanai, Hirotsugu; Tsuta, Koji; Sekimoto, Mitsugu; Sugie, Tomoharu

Yoshikawa, Katsuhiro; Ishida, Mitsuaki; Yanai, Hirotsugu; Tsuta, Koji; Sekimoto, Mitsugu; Sugie, Tomoharu.

Affiliation

Yoshikawa K; Department of Pathology and Clinical Laboratory, Kansai Medical University, 2-5-1, Shinmachi, Osaka, 573-1010, Hirakata City, Japan.
Ishida M; Department of Surgery, Kansai Medical University, 2-5-1, Shinmachi, Osaka, Hirakata City, Japan.
Yanai H; Department of Pathology and Clinical Laboratory, Kansai Medical University, 2-5-1, Shinmachi, Osaka, 573-1010, Hirakata City, Japan. ishidamt@hirakata.kmu.ac.jp.
Tsuta K; Department of Surgery, Kansai Medical University, 2-5-1, Shinmachi, Osaka, Hirakata City, Japan.
Sekimoto M; Department of Pathology and Clinical Laboratory, Kansai Medical University, 2-5-1, Shinmachi, Osaka, 573-1010, Hirakata City, Japan.
Sugie T; Department of Surgery, Kansai Medical University, 2-5-1, Shinmachi, Osaka, Hirakata City, Japan.

BMC Cancer ; 21(1): 239, 2021 Mar 06.

Article in En | MEDLINE | ID: mdl-33676425

Subject(s)

Cancer-Associated Fibroblasts/immunology; Neoplasm Recurrence, Local/epidemiology; Triple Negative Breast Neoplasms/mortality; Tumor Microenvironment/immunology; Adult; Aged; Aged, 80 and over; B7-H1 Antigen/analysis; B7-H1 Antigen/metabolism; Breast/immunology; Breast/pathology; Breast/surgery; Cancer-Associated Fibroblasts/metabolism; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Mastectomy; Middle Aged; Neoplasm Recurrence, Local/immunology; Neoplasm Recurrence, Local/prevention & control; Prognosis; Retrospective Studies; Triple Negative Breast Neoplasms/immunology; Triple Negative Breast Neoplasms/pathology; Triple Negative Breast Neoplasms/therapy

Key words

Cancer-associated fibroblasts; Overall survival; Programmed death ligand 1; Triple-negative breast cancer

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Microenvironment / Triple Negative Breast Neoplasms / Cancer-Associated Fibroblasts / Neoplasm Recurrence, Local Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Middle aged Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2021 Type: Article Affiliation country: Japan

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