Pharmacokinetics of UGN-101, a mitomycin-containing reverse thermal gel instilled via retrograde catheter for the treatment of low-grade upper tract urothelial carcinoma.

Shabsigh, Ahmad; Kleinmann, Nir; Smith, Angela B; Scherr, Douglas; Seltzer, Elyse; Schoenberg, Mark; Lerner, Seth P

Shabsigh, Ahmad; Kleinmann, Nir; Smith, Angela B; Scherr, Douglas; Seltzer, Elyse; Schoenberg, Mark; Lerner, Seth P.

Affiliation

Shabsigh A; Department of Urology, The Ohio State University Comprehensive Cancer Center, 300 W 10th Ave, Columbus, OH, 43210, USA. Ahmad.Shabsigh@osumc.edu.
Kleinmann N; Department of Urology, Sheba Medical Center, Ramat Gan, Israel.
Smith AB; Department of Urology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Scherr D; Department of Urology, Weill Medical College of Cornell University, New York, NY, USA.
Seltzer E; UroGen Pharma, New York, NY, USA.
Schoenberg M; UroGen Pharma, New York, NY, USA.
Lerner SP; Department of Urology, Albert Einstein College of Medicine, Bronx, NY, USA.

Cancer Chemother Pharmacol ; 87(6): 799-805, 2021 06.

Article in En | MEDLINE | ID: mdl-33677615

Subject(s)

Gels/pharmacokinetics; Mitomycin/pharmacokinetics; Mitomycin/therapeutic use; Urinary Tract/drug effects; Urologic Neoplasms/drug therapy; Aged; Aged, 80 and over; Biopsy; Catheters; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local/drug therapy; Neoplasm Recurrence, Local/pathology; Urinary Tract/pathology; Urologic Neoplasms/pathology; Urothelium/drug effects; Urothelium/pathology

Key words

Mitomycin; Pharmacokinetics; UGN-101; UTUC; Upper tract urothelial carcinoma

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Tract / Urologic Neoplasms / Mitomycin / Gels Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Cancer Chemother Pharmacol Year: 2021 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google