Predictors of reproductive and non-reproductive outcomes of gonadotropin mediated pubertal induction in male patients with congenital hypogonadotropic hypogonadism (CHH).

Cangiano, B; Goggi, G; Federici, S; Bresesti, C; Cotellessa, L; Guizzardi, F; Vezzoli, V; Duminuco, P; Persani, L; Bonomi, M

Cangiano, B; Goggi, G; Federici, S; Bresesti, C; Cotellessa, L; Guizzardi, F; Vezzoli, V; Duminuco, P; Persani, L; Bonomi, M.

Affiliation

Cangiano B; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
Goggi G; Department of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, IRCCS Istituto Auxologico Italiano, P.le Brescia 20, 20149, Milan, Italy.
Federici S; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
Bresesti C; Department of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, IRCCS Istituto Auxologico Italiano, P.le Brescia 20, 20149, Milan, Italy.
Cotellessa L; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
Guizzardi F; Department of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, IRCCS Istituto Auxologico Italiano, P.le Brescia 20, 20149, Milan, Italy.
Vezzoli V; Department of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, IRCCS Istituto Auxologico Italiano, P.le Brescia 20, 20149, Milan, Italy.
Duminuco P; Department of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, IRCCS Istituto Auxologico Italiano, P.le Brescia 20, 20149, Milan, Italy.
Persani L; Department of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, IRCCS Istituto Auxologico Italiano, P.le Brescia 20, 20149, Milan, Italy.
Bonomi M; Department of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, IRCCS Istituto Auxologico Italiano, P.le Brescia 20, 20149, Milan, Italy.

J Endocrinol Invest ; 44(11): 2445-2454, 2021 Nov.

Article in En | MEDLINE | ID: mdl-33738751

Subject(s)

Body Height/drug effects; Chorionic Gonadotropin/therapeutic use; Cryptorchidism; Follicle Stimulating Hormone/therapeutic use; Genetic Predisposition to Disease; Hypogonadism; Adult; Cryptorchidism/diagnosis; Cryptorchidism/etiology; Dose-Response Relationship, Drug; Gonadal Dysgenesis/drug therapy; Gonadal Dysgenesis/etiology; Gonadotropins/therapeutic use; High-Throughput Nucleotide Sequencing/methods; Humans; Hypogonadism/congenital; Hypogonadism/genetics; Hypogonadism/therapy; Male; Puberty/drug effects; Reproductive Health/statistics & numerical data; Semen Analysis/methods; Semen Analysis/statistics & numerical data; Testis; Time-to-Treatment/standards

Key words

Androgenization; Genetics; GnRH deficiency; Isolated hypogonadotropic hypogonadism; Puberty

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Body Height / Genetic Predisposition to Disease / Cryptorchidism / Follicle Stimulating Hormone / Chorionic Gonadotropin / Hypogonadism Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Humans / Male Language: En Journal: J Endocrinol Invest Year: 2021 Type: Article Affiliation country: Italy

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