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Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with ß-actin.
Tabusi, Mahebali; Thorsdottir, Sigrun; Lysandrou, Maria; Narciso, Ana Rita; Minoia, Melania; Srambickal, Chinmaya Venugopal; Widengren, Jerker; Henriques-Normark, Birgitta; Iovino, Federico.
Affiliation
  • Tabusi M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, BioClinicum J7:20, Stockholm, Sweden.
  • Thorsdottir S; Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
  • Lysandrou M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, BioClinicum J7:20, Stockholm, Sweden.
  • Narciso AR; Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
  • Minoia M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, BioClinicum J7:20, Stockholm, Sweden.
  • Srambickal CV; Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
  • Widengren J; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, BioClinicum J7:20, Stockholm, Sweden.
  • Henriques-Normark B; Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
  • Iovino F; Department of Molecular Biosciences, The Wenner-Gren Institutet, Stockholm University, Stockholm, Sweden.
PLoS Pathog ; 17(3): e1009432, 2021 03.
Article in En | MEDLINE | ID: mdl-33760879
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptolysins / Actins / Fimbriae Proteins / Virulence Factors / Meningitis, Pneumococcal / Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2021 Type: Article Affiliation country: Sweden
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptolysins / Actins / Fimbriae Proteins / Virulence Factors / Meningitis, Pneumococcal / Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2021 Type: Article Affiliation country: Sweden