De novo histidine biosynthesis protects Mycobacterium tuberculosis from host IFN-Î³ mediated histidine starvation.

Dwivedy, Abhisek; Ashraf, Anam; Jha, Bhavya; Kumar, Deepak; Agarwal, Nisheeth; Biswal, Bichitra K

Dwivedy, Abhisek; Ashraf, Anam; Jha, Bhavya; Kumar, Deepak; Agarwal, Nisheeth; Biswal, Bichitra K.

Affiliation

Dwivedy A; National Institute of Immunology, New Delhi, India.
Ashraf A; National Institute of Immunology, New Delhi, India.
Jha B; National Institute of Immunology, New Delhi, India.
Kumar D; National Institute of Immunology, New Delhi, India.
Agarwal N; Translational Health Science and Technology Institute, NCR Biotech Science Cluster, Faridabad, India.
Biswal BK; National Institute of Immunology, New Delhi, India. bbiswal@nii.ac.in.

Commun Biol ; 4(1): 410, 2021 03 25.

Article in En | MEDLINE | ID: mdl-33767335

Subject(s)

Histidine/biosynthesis; Host-Pathogen Interactions; Interferon-gamma/metabolism; Mycobacterium tuberculosis/metabolism; Mycobacterium tuberculosis/pathogenicity; Animals; Female; Histidine/deficiency; Humans; Mice; Mice, Inbred C57BL; RAW 264.7 Cells; Rabbits; Signal Transduction; THP-1 Cells; Virulence

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon-gamma / Host-Pathogen Interactions / Histidine / Mycobacterium tuberculosis Limits: Animals / Female / Humans Language: En Journal: Commun Biol Year: 2021 Type: Article Affiliation country: India

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