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CDER167, a dual inhibitor of URAT1 and GLUT9, is a novel and potent uricosuric candidate for the treatment of hyperuricemia.
Zhao, Ze-An; Jiang, Yu; Chen, Yan-Yu; Wu, Ting; Lan, Qun-Sheng; Li, Yong-Mei; Li, Lu; Yang, Yang; Lin, Cui-Ting; Cao, Ying; Zhou, Ping-Zheng; Guo, Jia-Yin; Tian, Yuan-Xin; Pang, Jian-Xin.
Affiliation
  • Zhao ZA; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Jiang Y; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Chen YY; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Wu T; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Lan QS; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Li YM; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Li L; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Yang Y; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Lin CT; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Cao Y; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Zhou PZ; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
  • Guo JY; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. g1227@smu.edu.cn.
  • Tian YX; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. tyx523@163.com.
  • Pang JX; Guangdong Provincial Key Laboratory of Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. pjx@smu.edu.cn.
Acta Pharmacol Sin ; 43(1): 121-132, 2022 Jan.
Article in En | MEDLINE | ID: mdl-33767379
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organic Anion Transporters / Organic Cation Transport Proteins / Hyperuricemia / Glucose Transport Proteins, Facilitative Limits: Humans Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2022 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organic Anion Transporters / Organic Cation Transport Proteins / Hyperuricemia / Glucose Transport Proteins, Facilitative Limits: Humans Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2022 Type: Article Affiliation country: China