Development of CDK4/6 Inhibitors: A Five Years Update.

Ammazzalorso, Alessandra; Agamennone, Mariangela; De Filippis, Barbara; Fantacuzzi, Marialuigia

Ammazzalorso, Alessandra; Agamennone, Mariangela; De Filippis, Barbara; Fantacuzzi, Marialuigia.

Affiliation

Ammazzalorso A; Unit of Medicinal Chemistry, Department of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.
Agamennone M; Unit of Medicinal Chemistry, Department of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.
De Filippis B; Unit of Medicinal Chemistry, Department of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.
Fantacuzzi M; Unit of Medicinal Chemistry, Department of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.

Molecules ; 26(5)2021 Mar 09.

Article in En | MEDLINE | ID: mdl-33803309

Subject(s)

Cyclin-Dependent Kinase 4/antagonists & inhibitors; Cyclin-Dependent Kinase 6/antagonists & inhibitors; Protein Kinase Inhibitors/pharmacology; Antineoplastic Combined Chemotherapy Protocols/pharmacology; Aromatase Inhibitors/pharmacology; Breast Neoplasms/drug therapy; Female; Humans; Molecular Targeted Therapy/trends

Key words

PROTACs; cancer; cyclin-dependent kinase; resistance; small molecule inhibitors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Cyclin-Dependent Kinase 4 / Cyclin-Dependent Kinase 6 Limits: Female / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2021 Type: Article Affiliation country: Italy

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