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Chitinase 3-like 1 is a profibrogenic factor overexpressed in the aging liver and in patients with liver cirrhosis.
Nishimura, Norihisa; De Battista, Davide; McGivern, David R; Engle, Ronald E; Tice, Ashley; Fares-Gusmao, Rafaelle; Kabat, Juraj; Pomerenke, Anna; Nguyen, Hanh; Sato, Shinya; Bock, Kevin W; Moore, Ian N; Kleiner, David E; Zamboni, Fausto; Alter, Harvey J; Govindarajan, Sugantha; Farci, Patrizia.
Affiliation
  • Nishimura N; Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892.
  • De Battista D; Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892.
  • McGivern DR; Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD 20993.
  • Engle RE; Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892.
  • Tice A; Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892.
  • Fares-Gusmao R; Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD 20993.
  • Kabat J; Biological Imaging Facility Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892.
  • Pomerenke A; Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892.
  • Nguyen H; Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892.
  • Sato S; Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892.
  • Bock KW; Infectious Disease Pathogenesis Section, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892.
  • Moore IN; Infectious Disease Pathogenesis Section, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892.
  • Kleiner DE; Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, MD 20892.
  • Zamboni F; Liver Transplantation Center, Azienda Ospedaliera Brotzu, 09134 Cagliari, Italy.
  • Alter HJ; Department of Transfusion Medicine, Clinical Center, NIH, Bethesda, MD 20892; halter@dtm.cc.nih.gov patrizia.farci@nih.gov.
  • Govindarajan S; Department of Pathology, Rancho Los Amigos Hospital, University of Southern California, Los Angeles, CA 90242.
  • Farci P; Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892; halter@dtm.cc.nih.gov patrizia.farci@nih.gov.
Proc Natl Acad Sci U S A ; 118(17)2021 04 27.
Article in En | MEDLINE | ID: mdl-33888584

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chitinase-3-Like Protein 1 / Liver Cirrhosis Type of study: Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chitinase-3-Like Protein 1 / Liver Cirrhosis Type of study: Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Type: Article