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A survey of the kinome pharmacopeia reveals multiple scaffolds and targets for the development of novel anthelmintics.
Knox, Jessica; Joly, Nicolas; Linossi, Edmond M; Carmona-Negrón, José A; Jura, Natalia; Pintard, Lionel; Zuercher, William; Roy, Peter J.
Affiliation
  • Knox J; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada.
  • Joly N; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
  • Linossi EM; Programme Équipe Labellisée Ligue Contre Le Cancer, Institut Jacques Monod, UMR7592, Université de Paris, CNRS, Paris, France.
  • Carmona-Negrón JA; Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, 94158, USA.
  • Jura N; Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, 94158, USA.
  • Pintard L; Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, 94158, USA.
  • Zuercher W; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.
  • Roy PJ; Programme Équipe Labellisée Ligue Contre Le Cancer, Institut Jacques Monod, UMR7592, Université de Paris, CNRS, Paris, France.
Sci Rep ; 11(1): 9161, 2021 04 28.
Article in En | MEDLINE | ID: mdl-33911106
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Caenorhabditis elegans / Protein Kinase Inhibitors / Drug Evaluation, Preclinical / Anthelmintics Type of study: Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2021 Type: Article Affiliation country: Canada
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Caenorhabditis elegans / Protein Kinase Inhibitors / Drug Evaluation, Preclinical / Anthelmintics Type of study: Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2021 Type: Article Affiliation country: Canada