Endometrial epithelial-mesenchymal transition (EMT) by menstruation-related inflammatory factors during hypoxia.

Kusama, K; Fukushima, Y; Yoshida, K; Sakakibara, H; Tsubata, N; Yoshie, M; Kojima, J; Nishi, H; Tamura, K

Kusama, K; Fukushima, Y; Yoshida, K; Sakakibara, H; Tsubata, N; Yoshie, M; Kojima, J; Nishi, H; Tamura, K.

Affiliation

Kusama K; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.
Fukushima Y; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.
Yoshida K; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.
Sakakibara H; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.
Tsubata N; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.
Yoshie M; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.
Kojima J; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo 160-0023, Japan.
Nishi H; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo 160-0023, Japan.
Tamura K; Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.

Mol Hum Reprod ; 27(6)2021 05 29.

Article in En | MEDLINE | ID: mdl-33983443

Subject(s)

Cell Hypoxia; Endometriosis/etiology; Endometrium/pathology; Epithelial-Mesenchymal Transition; Menstruation Disturbances/pathology; Menstruation/physiology; Adult; Biomarkers; Cell Culture Techniques, Three Dimensional; Cell Movement/drug effects; Cells, Cultured; Chemokine CXCL12/metabolism; Chemokine CXCL12/pharmacology; Dinoprostone/pharmacology; Endometriosis/pathology; Endometrium/metabolism; Epithelial Cells/drug effects; Estradiol/pharmacology; Female; Gene Expression; Humans; Inflammation; Inflammation Mediators/metabolism; Menstruation Disturbances/metabolism; Spheroids, Cellular; Stromal Cells/drug effects; Thrombin/pharmacology

Key words

CXCL12; CXCR4; endometrial cell; endometriosis; epithelialmesenchymal transition; hypoxia

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Hypoxia / Endometriosis / Endometrium / Epithelial-Mesenchymal Transition / Menstruation / Menstruation Disturbances Type of study: Prognostic_studies Limits: Adult / Female / Humans Language: En Journal: Mol Hum Reprod Journal subject: BIOLOGIA MOLECULAR / MEDICINA REPRODUTIVA Year: 2021 Type: Article Affiliation country: Japan

Fulltext

XML

PubMed Links

Search on Google