Proto-oncoprotein Zbtb7c and SIRT1 repression: implications in high-fat diet-induced and age-dependent obesity.

Choi, Won-Il; Yoon, Jae-Hyun; Choi, Seo-Hyun; Jeon, Bu-Nam; Kim, Hail; Hur, Man-Wook

Choi, Won-Il; Yoon, Jae-Hyun; Choi, Seo-Hyun; Jeon, Bu-Nam; Kim, Hail; Hur, Man-Wook.

Affiliation

Choi WI; Brain Korea FOUR Project for Medical Science, Department of Biochemistry & Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul, 03722, Korea.
Yoon JH; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, DaeJeon, 34141, Korea.
Choi SH; Brain Korea FOUR Project for Medical Science, Department of Biochemistry & Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul, 03722, Korea.
Jeon BN; Brain Korea FOUR Project for Medical Science, Department of Biochemistry & Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul, 03722, Korea.
Kim H; Brain Korea FOUR Project for Medical Science, Department of Biochemistry & Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul, 03722, Korea.
Hur MW; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, DaeJeon, 34141, Korea.

Exp Mol Med ; 53(5): 917-932, 2021 05.

Article in En | MEDLINE | ID: mdl-34017061

Subject(s)

Aging/genetics; Aging/metabolism; Diet, High-Fat; Intracellular Signaling Peptides and Proteins/genetics; Obesity/etiology; Obesity/metabolism; Sirtuin 1/genetics; 3T3-L1 Cells; Adipocytes/cytology; Adipocytes/metabolism; Animals; Biomarkers; Diet, High-Fat/adverse effects; Disease Models, Animal; Disease Susceptibility; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Intracellular Signaling Peptides and Proteins/metabolism; Lipid Metabolism; Mice; Mice, Knockout; Obesity/pathology; Oncogene Proteins/genetics; Oncogene Proteins/metabolism; Protein Binding; Response Elements; Sirtuin 1/metabolism; Transcription Factors/metabolism; Tumor Suppressor Protein p53/genetics; Tumor Suppressor Protein p53/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Intracellular Signaling Peptides and Proteins / Sirtuin 1 / Diet, High-Fat / Obesity Type of study: Prognostic_studies Limits: Animals Language: En Journal: Exp Mol Med Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2021 Type: Article

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