Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4.

Salama, Abeer; Mahmoud, Hend Abd-AlHakim; Kandeil, Mohamed Ahmed; Khalaf, Marwa Mahmoud

Salama, Abeer; Mahmoud, Hend Abd-AlHakim; Kandeil, Mohamed Ahmed; Khalaf, Marwa Mahmoud.

Affiliation

Salama A; Department of Pharmacology, National Research Centre, Cairo, Egypt.
Mahmoud HA; Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
Kandeil MA; Department of Biochemistry, Faculty of Veterinary medicine, Beni-Suef University, Beni Suef, Egypt.
Khalaf MM; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni Suef, Egypt.

Immunopharmacol Immunotoxicol ; 43(3): 309-318, 2021 Jun.

Article in En | MEDLINE | ID: mdl-34032546

Subject(s)

Camphor/pharmacology; Ciprofloxacin/adverse effects; Depression; NF-E2-Related Factor 2/metabolism; Neuroprotective Agents/pharmacology; Toll-Like Receptor 4/metabolism; Animals; COVID-19/metabolism; COVID-19/pathology; Ciprofloxacin/pharmacology; Depression/chemically induced; Depression/drug therapy; Depression/metabolism; Male; Rats; Rats, Wistar; SARS-CoV-2/metabolism; COVID-19 Drug Treatment

Key words

Depression; Nrf-2; P190-RHO GTP protein; TLR4; camphor; neurotransmitters

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Camphor / Ciprofloxacin / Neuroprotective Agents / Depression / NF-E2-Related Factor 2 / Toll-Like Receptor 4 Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Immunopharmacol Immunotoxicol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / TOXICOLOGIA Year: 2021 Type: Article Affiliation country: Egypt

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