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Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease.
Zhang, Shengnan; Liu, Yu-Qing; Jia, Chunyu; Lim, Yeh-Jun; Feng, Guoqin; Xu, Enquan; Long, Houfang; Kimura, Yasuyoshi; Tao, Youqi; Zhao, Chunyu; Wang, Chuchu; Liu, Zhenying; Hu, Jin-Jian; Ma, Meng-Rong; Liu, Zhijun; Jiang, Lin; Li, Dan; Wang, Renxiao; Dawson, Valina L; Dawson, Ted M; Li, Yan-Mei; Mao, Xiaobo; Liu, Cong.
Affiliation
  • Zhang S; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China.
  • Liu YQ; Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
  • Jia C; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China.
  • Lim YJ; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Feng G; Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
  • Xu E; State Key Laboratory of Bio-organic Chemistry and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
  • Long H; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
  • Kimura Y; Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
  • Tao Y; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
  • Zhao C; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China.
  • Wang C; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Liu Z; Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
  • Hu JJ; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
  • Ma MR; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai 200030, China.
  • Liu Z; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China.
  • Jiang L; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Li D; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China.
  • Wang R; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Dawson VL; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China.
  • Dawson TM; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Li YM; Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
  • Mao X; Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
  • Liu C; National Center for Protein Science Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China.
Proc Natl Acad Sci U S A ; 118(26)2021 06 29.
Article in En | MEDLINE | ID: mdl-34172566

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Antigens, CD / Amyloid beta-Protein Precursor / Alpha-Synuclein / Amyloid Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Type: Article Affiliation country: China

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Antigens, CD / Amyloid beta-Protein Precursor / Alpha-Synuclein / Amyloid Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Type: Article Affiliation country: China