Transmembrane Protease TMPRSS4 Promotes the Formation and Development of Mismatch Repair Deficient Colon Cancer Liver Metastasis.

Yang, Y S; Wen, D; Zhao, X F

Yang, Y S; Wen, D; Zhao, X F.

Affiliation

Yang YS; Department of General Surgery, Dalian University Affiliated Xinhua Hospital, Dalian, China.
Wen D; Department of General Surgery, Dalian University Affiliated Xinhua Hospital, Dalian, China.
Zhao XF; Department of General Surgery, Dalian University Affiliated Xinhua Hospital, Dalian, China. zoserbong@163.com.

Bull Exp Biol Med ; 171(2): 242-246, 2021 May.

Article in En | MEDLINE | ID: mdl-34173918

Subject(s)

Colonic Neoplasms/pathology; Liver Neoplasms/secondary; Membrane Proteins/physiology; Serine Endopeptidases/physiology; Animals; Brain Neoplasms/complications; Brain Neoplasms/genetics; Brain Neoplasms/pathology; Cell Movement/genetics; Cell Transformation, Neoplastic/genetics; Colonic Neoplasms/genetics; Colorectal Neoplasms/complications; Colorectal Neoplasms/genetics; Colorectal Neoplasms/pathology; DNA Mismatch Repair/genetics; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms/genetics; Membrane Proteins/genetics; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Syndromes, Hereditary/complications; Neoplastic Syndromes, Hereditary/genetics; Neoplastic Syndromes, Hereditary/pathology; Serine Endopeptidases/genetics; Tumor Cells, Cultured

Key words

BALB/c nude mouse; DNA mismatch repair deficiencies; TMPRSS4; colon cancer liver metastasis; metastasis-promoting effect

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine Endopeptidases / Colonic Neoplasms / Liver Neoplasms / Membrane Proteins Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Bull Exp Biol Med Year: 2021 Type: Article Affiliation country: China

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