Assessment of Paroxetine Molecular Interactions with Selected Monoamine and Î³-Aminobutyric Acid Transporters.

Kowalska, Magdalena; Fijalkowski, Lukasz; Nowaczyk, Alicja

Kowalska, Magdalena; Fijalkowski, Lukasz; Nowaczyk, Alicja.

Affiliation

Kowalska M; Department of Organic Chemistry, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 2 dr. A. Jurasza St., 85-094 Bydgoszcz, Poland.
Fijalkowski L; Department of Organic Chemistry, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 2 dr. A. Jurasza St., 85-094 Bydgoszcz, Poland.
Nowaczyk A; Department of Organic Chemistry, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 2 dr. A. Jurasza St., 85-094 Bydgoszcz, Poland.

Int J Mol Sci ; 22(12)2021 Jun 11.

Article in En | MEDLINE | ID: mdl-34208199

Subject(s)

GABA Plasma Membrane Transport Proteins/metabolism; Paroxetine/metabolism; Vesicular Monoamine Transport Proteins/metabolism; Animals; Binding Sites; CHO Cells; Cricetulus; Humans; Molecular Docking Simulation; Neurotransmitter Agents/chemistry; Neurotransmitter Agents/metabolism; Paroxetine/chemistry

Key words

antidepressant; monoamine and GABA neurotransmitters; monoamine transporters (MAT); neurogenesis; paroxetine (PRX); Î³-Aminobutyric acid transporter (GAT)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paroxetine / Vesicular Monoamine Transport Proteins / GABA Plasma Membrane Transport Proteins Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2021 Type: Article Affiliation country: Poland

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