Anticonvulsant effectiveness of scopolamine against soman-induced seizures in African green monkeys.

McDonough, John H; McMonagle, Joseph D; Capacio, Benedict R

McDonough, John H; McMonagle, Joseph D; Capacio, Benedict R.

Affiliation

McDonough JH; Neuroscience Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD, USA.
McMonagle JD; Neuroscience Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD, USA.
Capacio BR; Medical Toxicology Research Division, Pharmaceutical Sciences Department, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD, USA.

Drug Chem Toxicol ; 45(5): 2185-2192, 2022 Sep.

Article in En | MEDLINE | ID: mdl-34251950

Subject(s)

Nerve Agents; Soman; Animals; Anticonvulsants/toxicity; Chlorocebus aethiops; Cholinesterase Inhibitors/toxicity; Electroencephalography; Guinea Pigs; Male; Nerve Agents/toxicity; Rats; Scopolamine/toxicity; Seizures/chemically induced; Seizures/drug therapy; Seizures/prevention & control; Soman/therapeutic use; Soman/toxicity

Key words

African green monkey; Nerve agent; anticonvulsant; scopolamine; seizure; soman

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Soman / Nerve Agents Limits: Animals Language: En Journal: Drug Chem Toxicol Year: 2022 Type: Article Affiliation country: United States

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